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89 results
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Regulatory T cells in melanoma: the final hurdle towards effective immunotherapy?
Jacobs JF, Nierkens S, Figdor CG, de Vries IJ, Adema GJ. Jacobs JF, et al. Lancet Oncol. 2012 Jan;13(1):e32-42. doi: 10.1016/S1470-2045(11)70155-3. Lancet Oncol. 2012. PMID: 22225723 Review.
Dendritic Cells as Vaccines: Key Regulators of Tolerance and Immunity.
Tel J, Benitez-Ribas D, Janssen EM, Smits EL, Jacobs JF. Tel J, et al. Among authors: jacobs jf. Mediators Inflamm. 2016;2016:5789725. doi: 10.1155/2016/5789725. Epub 2016 May 31. Mediators Inflamm. 2016. PMID: 27340343 Free PMC article. No abstract available.
Monitoring of dynamic changes in Keyhole Limpet Hemocyanin (KLH)-specific B cells in KLH-vaccinated cancer patients.
Wimmers F, de Haas N, Scholzen A, Schreibelt G, Simonetti E, Eleveld MJ, Brouwers HM, Beldhuis-Valkis M, Joosten I, de Jonge MI, Gerritsen WR, de Vries IJ, Diavatopoulos DA, Jacobs JF. Wimmers F, et al. Among authors: jacobs jf. Sci Rep. 2017 Mar 7;7:43486. doi: 10.1038/srep43486. Sci Rep. 2017. PMID: 28344338 Free PMC article. Clinical Trial.
Humoral and cellular immune responses after influenza vaccination in patients with postcancer fatigue.
Prinsen H, van Laarhoven HW, Pots JM, Duiveman-de Boer T, Mulder SF, van Herpen CM, Jacobs JF, Leer JW, Bleijenberg G, Stelma FF, Torensma R, de Vries IJ. Prinsen H, et al. Among authors: jacobs jf. Hum Vaccin Immunother. 2015;11(7):1634-40. doi: 10.1080/21645515.2015.1040207. Hum Vaccin Immunother. 2015. PMID: 25996472 Free PMC article.
Early identification of antigen-specific immune responses in vivo by [18F]-labeled 3'-fluoro-3'-deoxy-thymidine ([18F]FLT) PET imaging.
Aarntzen EH, Srinivas M, De Wilt JH, Jacobs JF, Lesterhuis WJ, Windhorst AD, Troost EG, Bonenkamp JJ, van Rossum MM, Blokx WA, Mus RD, Boerman OC, Punt CJ, Figdor CG, Oyen WJ, de Vries IJ. Aarntzen EH, et al. Among authors: jacobs jf. Proc Natl Acad Sci U S A. 2011 Nov 8;108(45):18396-9. doi: 10.1073/pnas.1113045108. Epub 2011 Oct 24. Proc Natl Acad Sci U S A. 2011. PMID: 22025695 Free PMC article.
PD-1 blockade augments Th1 and Th17 and suppresses Th2 responses in peripheral blood from patients with prostate and advanced melanoma cancer.
Dulos J, Carven GJ, van Boxtel SJ, Evers S, Driessen-Engels LJ, Hobo W, Gorecka MA, de Haan AF, Mulders P, Punt CJ, Jacobs JF, Schalken JA, Oosterwijk E, van Eenennaam H, Boots AM. Dulos J, et al. Among authors: jacobs jf. J Immunother. 2012 Feb-Mar;35(2):169-78. doi: 10.1097/CJI.0b013e318247a4e7. J Immunother. 2012. PMID: 22306905
Humoral anti-KLH responses in cancer patients treated with dendritic cell-based immunotherapy are dictated by different vaccination parameters.
Aarntzen EH, de Vries IJ, Göertz JH, Beldhuis-Valkis M, Brouwers HM, van de Rakt MW, van der Molen RG, Punt CJ, Adema GJ, Tacken PJ, Joosten I, Jacobs JF. Aarntzen EH, et al. Among authors: jacobs jf. Cancer Immunol Immunother. 2012 Nov;61(11):2003-11. doi: 10.1007/s00262-012-1263-z. Epub 2012 Apr 21. Cancer Immunol Immunother. 2012. PMID: 22527252 Free PMC article.
Targeting CD4(+) T-helper cells improves the induction of antitumor responses in dendritic cell-based vaccination.
Aarntzen EH, De Vries IJ, Lesterhuis WJ, Schuurhuis D, Jacobs JF, Bol K, Schreibelt G, Mus R, De Wilt JH, Haanen JB, Schadendorf D, Croockewit A, Blokx WA, Van Rossum MM, Kwok WW, Adema GJ, Punt CJ, Figdor CG. Aarntzen EH, et al. Among authors: jacobs jf. Cancer Res. 2013 Jan 1;73(1):19-29. doi: 10.1158/0008-5472.CAN-12-1127. Epub 2012 Oct 18. Cancer Res. 2013. PMID: 23087058 Clinical Trial.
Skin-test infiltrating lymphocytes early predict clinical outcome of dendritic cell-based vaccination in metastatic melanoma.
Aarntzen EH, Bol K, Schreibelt G, Jacobs JF, Lesterhuis WJ, Van Rossum MM, Adema GJ, Figdor CG, Punt CJ, De Vries IJ. Aarntzen EH, et al. Among authors: jacobs jf. Cancer Res. 2012 Dec 1;72(23):6102-10. doi: 10.1158/0008-5472.CAN-12-2479. Epub 2012 Sep 24. Cancer Res. 2012. PMID: 23010076
Vaccination with mRNA-electroporated dendritic cells induces robust tumor antigen-specific CD4+ and CD8+ T cells responses in stage III and IV melanoma patients.
Aarntzen EH, Schreibelt G, Bol K, Lesterhuis WJ, Croockewit AJ, de Wilt JH, van Rossum MM, Blokx WA, Jacobs JF, Duiveman-de Boer T, Schuurhuis DH, Mus R, Thielemans K, de Vries IJ, Figdor CG, Punt CJ, Adema GJ. Aarntzen EH, et al. Among authors: jacobs jf. Clin Cancer Res. 2012 Oct 1;18(19):5460-70. doi: 10.1158/1078-0432.CCR-11-3368. Epub 2012 Aug 15. Clin Cancer Res. 2012. PMID: 22896657
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