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Plasma neurofilament light chain and amyloid-β are associated with the kynurenine pathway metabolites in preclinical Alzheimer's disease.
Chatterjee P, Zetterberg H, Goozee K, Lim CK, Jacobs KR, Ashton NJ, Hye A, Pedrini S, Sohrabi HR, Shah T, Asih PR, Dave P, Shen K, Taddei K, Lovejoy DB, Guillemin GJ, Blennow K, Martins RN. Chatterjee P, et al. Among authors: jacobs kr. J Neuroinflammation. 2019 Oct 10;16(1):186. doi: 10.1186/s12974-019-1567-4. J Neuroinflammation. 2019. PMID: 31601232 Free PMC article.
Systemic perturbations of the kynurenine pathway precede progression to dementia independently of amyloid-β.
Cespedes M, Jacobs KR, Maruff P, Rembach A, Fowler CJ, Trounson B, Pertile KK, Rumble RL, Rainey-Smith SR, Rowe CC, Villemagne VL, Bourgeat P, Lim CK, Chatterjee P, Martins RN, Ittner A, Masters CL, Doecke JD, Guillemin GJ, Lovejoy DB. Cespedes M, et al. Among authors: jacobs kr. Neurobiol Dis. 2022 Sep;171:105783. doi: 10.1016/j.nbd.2022.105783. Epub 2022 Jun 5. Neurobiol Dis. 2022. PMID: 35675895 Free article.
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