Jacobs T - Search Results

1

A latent pharmacokinetic time profile to model dose-response survival data.

Jacobs T, Straetemans R, Molenberghs G, Adriaan Bouwknecht J, Bijnens L. Jacobs T, et al. J Biopharm Stat. 2010 Jul;20(4):759-67. doi: 10.1080/10543401003618249. J Biopharm Stat. 2010. PMID: 20496204

2

Combined models for data from in vitro-in vivo correlation experiments.

Jacobs T, Rossenu S, Dunne A, Molenberghs G, Straetemans R, Bijnens L. Jacobs T, et al. J Biopharm Stat. 2008;18(6):1197-211. doi: 10.1080/10543400802369061. J Biopharm Stat. 2008. PMID: 18991117

3

A Bayesian K-PD model for synergy: A case study.

La Gamba F, Jacobs T, Geys H, Ver Donck L, Faes C. La Gamba F, et al. Among authors: jacobs t. Pharm Stat. 2018 Nov;17(6):674-684. doi: 10.1002/pst.1887. Epub 2018 Jul 19. Pharm Stat. 2018. PMID: 30027596

4

Bayesian sequential integration within a preclinical pharmacokinetic and pharmacodynamic modeling framework: Lessons learned.

La Gamba F, Jacobs T, Geys H, Jaki T, Serroyen J, Ursino M, Russu A, Faes C. La Gamba F, et al. Among authors: jacobs t. Pharm Stat. 2019 Jul;18(4):486-506. doi: 10.1002/pst.1941. Epub 2019 Apr 1. Pharm Stat. 2019. PMID: 30932327

5

Comparing sampling methods for pharmacokinetic studies using model averaged derived parameters.

Barnett HY, Geys H, Jacobs T, Jaki T. Barnett HY, et al. Among authors: jacobs t. Stat Med. 2017 Nov 30;36(27):4301-4315. doi: 10.1002/sim.7436. Epub 2017 Aug 8. Stat Med. 2017. PMID: 28786135

6

Including information on the therapeutic window in bioequivalence acceptance.

Jacobs T, De Ridder F, Rusch S, Van Peer A, Molenberghs G, Bijnens L. Jacobs T, et al. Pharm Res. 2008 Nov;25(11):2628-38. doi: 10.1007/s11095-008-9680-6. Epub 2008 Jul 18. Pharm Res. 2008. PMID: 18636320

7

The effect of Lidocaine on the viability of cultivated mature human cartilage cells: an in vitro study.

Jacobs TF, Vansintjan PS, Roels N, Herregods SS, Verbruggen G, Herregods LL, Almqvist KF. Jacobs TF, et al. Knee Surg Sports Traumatol Arthrosc. 2011 Jul;19(7):1206-13. doi: 10.1007/s00167-011-1420-5. Epub 2011 Feb 11. Knee Surg Sports Traumatol Arthrosc. 2011. PMID: 21311864

8

A proposal for a new PhD level curriculum on quantitative methods for drug development.

Jaki T, Gordon A, Forster P, Bijnens L, Bornkamp B, Brannath W, Fontana R, Gasparini M, Hampson LV, Jacobs T, Jones B, Paoletti X, Posch M, Titman A, Vonk R, Koenig F. Jaki T, et al. Among authors: jacobs t. Pharm Stat. 2018 Sep;17(5):593-606. doi: 10.1002/pst.1873. Epub 2018 Jul 9. Pharm Stat. 2018. PMID: 29984474 Free PMC article.

9

Replication capacity of minority variants in viral populations can affect the assessment of resistance in HCV chimeric replicon phenotyping assays.

Verbinnen T, Jacobs T, Vijgen L, Ceulemans H, Neyts J, Fanning G, Lenz O. Verbinnen T, et al. Among authors: jacobs t. J Antimicrob Chemother. 2012 Oct;67(10):2327-37. doi: 10.1093/jac/dks234. Epub 2012 Jun 21. J Antimicrob Chemother. 2012. PMID: 22723600

10

Comparison of two different methods for measurement of amyloid-β peptides in cerebrospinal fluid after BACE1 inhibition in a dog model.

Borghys H, Jacobs T, Van Broeck B, Dillen L, Dhuyvetter D, Gijsen H, Mercken M. Borghys H, et al. Among authors: jacobs t. J Alzheimers Dis. 2014;38(1):39-48. doi: 10.3233/JAD-130599. J Alzheimers Dis. 2014. PMID: 23948925

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