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Characterization of large deletion mutants of Mycobacterium tuberculosis selected for isoniazid resistance.
Vilchèze C, Saranathan R, Weinrick B, Jacobs WR Jr. Vilchèze C, et al. Among authors: jacobs wr jr. Antimicrob Agents Chemother. 2020 Jul 6:AAC.00792-20. doi: 10.1128/AAC.00792-20. Online ahead of print. Antimicrob Agents Chemother. 2020. PMID: 32631825
3-(Phenethylamino)demethyl(oxy)aaptamine as an anti-dormant mycobacterial substance: Isolation, evaluation and total synthesis.
Sumii Y, Kotoku N, Han C, Kamiya K, Setiawan A, Vilchèze C, Jacobs WR Jr, Arai M. Sumii Y, et al. Among authors: jacobs wr jr. Tetrahedron Lett. 2020 May 28;61(22):151924. doi: 10.1016/j.tetlet.2020.151924. Epub 2020 Apr 11. Tetrahedron Lett. 2020. PMID: 32577043
Exploiting Pre-Existing CD4+ T Cell Help from Bacille Calmette-Guérin Vaccination to Improve Antiviral Antibody Responses.
Ng TW, Wirchnianski AS, Wec AZ, Fels JM, Johndrow CT, Saunders KO, Liao HX, Chan J, Jacobs WR Jr, Chandran K, Porcelli SA. Ng TW, et al. Among authors: jacobs wr jr. J Immunol. 2020 Jul 15;205(2):425-437. doi: 10.4049/jimmunol.2000191. Epub 2020 Jun 8. J Immunol. 2020. PMID: 32513849
A Single-Cycle Glycoprotein D Deletion Viral Vaccine Candidate, ΔgD-2, Elicits Polyfunctional Antibodies That Protect against Ocular Herpes Simplex Virus.
Ramsey NLM, Visciano M, Hunte R, Loh LN, Burn Aschner C, Jacobs WR Jr, Herold BC. Ramsey NLM, et al. Among authors: jacobs wr jr. J Virol. 2020 Jun 16;94(13):e00335-20. doi: 10.1128/JVI.00335-20. Print 2020 Jun 16. J Virol. 2020. PMID: 32295919
Loss of phenotypic inheritance associated with ydcI mutation leads to increased frequency of small, slow persisters in Escherichia coli.
Hingley-Wilson SM, Ma N, Hu Y, Casey R, Bramming A, Curry RJ, Tang HL, Wu H, Butler RE, Jacobs WR Jr, Rocco A, McFadden J. Hingley-Wilson SM, et al. Among authors: jacobs wr jr. Proc Natl Acad Sci U S A. 2020 Feb 25;117(8):4152-4157. doi: 10.1073/pnas.1914741117. Epub 2020 Feb 6. Proc Natl Acad Sci U S A. 2020. PMID: 32029596 Free PMC article.
High-dose ascorbic acid synergizes with anti-PD1 in a lymphoma mouse model.
Luchtel RA, Bhagat T, Pradhan K, Jacobs WR Jr, Levine M, Verma A, Shenoy N. Luchtel RA, et al. Among authors: jacobs wr jr. Proc Natl Acad Sci U S A. 2020 Jan 21;117(3):1666-1677. doi: 10.1073/pnas.1908158117. Epub 2020 Jan 7. Proc Natl Acad Sci U S A. 2020. PMID: 31911474 Free PMC article.
Helicobacter pylori Infections in the Bronx, New York: Surveying Antibiotic Susceptibility and Strain Lineage by Whole-Genome Sequencing.
Saranathan R, Levi MH, Wattam AR, Malek A, Asare E, Behin DS, Pan DH, Jacobs WR Jr, Szymczak WA. Saranathan R, et al. Among authors: jacobs wr jr. J Clin Microbiol. 2020 Feb 24;58(3):e01591-19. doi: 10.1128/JCM.01591-19. Print 2020 Feb 24. J Clin Microbiol. 2020. PMID: 31801839
Derailing the aspartate pathway of Mycobacterium tuberculosis to eradicate persistent infection.
Hasenoehrl EJ, Rae Sajorda D, Berney-Meyer L, Johnson S, Tufariello JM, Fuhrer T, Cook GM, Jacobs WR Jr, Berney M. Hasenoehrl EJ, et al. Among authors: jacobs wr jr. Nat Commun. 2019 Sep 16;10(1):4215. doi: 10.1038/s41467-019-12224-3. Nat Commun. 2019. PMID: 31527595 Free PMC article.
Genome-wide mutational biases fuel transcriptional diversity in the Mycobacterium tuberculosis complex.
Chiner-Oms Á, Berney M, Boinett C, González-Candelas F, Young DB, Gagneux S, Jacobs WR Jr, Parkhill J, Cortes T, Comas I. Chiner-Oms Á, et al. Among authors: jacobs wr jr. Nat Commun. 2019 Sep 5;10(1):3994. doi: 10.1038/s41467-019-11948-6. Nat Commun. 2019. PMID: 31488832 Free PMC article.
Generation of IL-3-Secreting CD4+ T Cells by Microbial Challenge at Skin and Mucosal Barriers.
Kunnath-Velayudhan S, Goldberg MF, Saini NK, Ng TW, Arora P, Johndrow CT, Saavedra-Avila NA, Johnson AJ, Xu J, Kim J, Khajoueinejad N, Petro CD, Herold BC, Lauvau G, Chan J, Jacobs WR Jr, Porcelli SA. Kunnath-Velayudhan S, et al. Among authors: jacobs wr jr. Immunohorizons. 2019 May 16;3(5):161-171. doi: 10.4049/immunohorizons.1900028. Immunohorizons. 2019. PMID: 31356170 Free PMC article.
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