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DNA hypomethylation leads to elevated mutation rates.
Chen RZ, Pettersson U, Beard C, Jackson-Grusby L, Jaenisch R. Chen RZ, et al. Nature. 1998 Sep 3;395(6697):89-93. doi: 10.1038/25779. Nature. 1998. PMID: 9738504
An X-linked human collagen transgene escapes X inactivation in a subset of cells.
Wu H, Fässler R, Schnieke A, Barker D, Lee KH, Chapman V, Francke U, Jaenisch R. Wu H, et al. Development. 1992 Nov;116(3):687-95. Development. 1992. PMID: 1289060
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