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Mechanisms of immune evasion by tumors.
Drake CG, Jaffee E, Pardoll DM. Drake CG, et al. Adv Immunol. 2006;90:51-81. doi: 10.1016/S0065-2776(06)90002-9. Adv Immunol. 2006. PMID: 16730261 Review.
Use of murine models of cytokine-secreting tumor vaccines to study feasibility and toxicity issues critical to designing clinical trials.
Jaffee EM, Lazenby A, Meurer J, Marshall F, Hauda KM, Counts C, Hurwitz H, Simons JW, Levitsky HI, Pardoll DM. Jaffee EM, et al. J Immunother Emphasis Tumor Immunol. 1995 Jul;18(1):1-9. doi: 10.1097/00002371-199507000-00001. J Immunother Emphasis Tumor Immunol. 1995. PMID: 8535565 No abstract available.
The immunodominant major histocompatibility complex class I-restricted antigen of a murine colon tumor derives from an endogenous retroviral gene product.
Huang AY, Gulden PH, Woods AS, Thomas MC, Tong CD, Wang W, Engelhard VH, Pasternack G, Cotter R, Hunt D, Pardoll DM, Jaffee EM. Huang AY, et al. Proc Natl Acad Sci U S A. 1996 Sep 3;93(18):9730-5. doi: 10.1073/pnas.93.18.9730. Proc Natl Acad Sci U S A. 1996. PMID: 8790399 Free PMC article.
Enhanced immune priming with spatial distribution of paracrine cytokine vaccines.
Jaffee EM, Thomas MC, Huang AY, Hauda KM, Levitsky HI, Pardoll DM. Jaffee EM, et al. J Immunother Emphasis Tumor Immunol. 1996 May;19(3):176-83. doi: 10.1097/00002371-199605000-00002. J Immunother Emphasis Tumor Immunol. 1996. PMID: 8811492
Systemic and local paracrine cytokine therapies using transduced tumor cells are synergistic in treating intracranial tumors.
Thompson RC, Pardoll DM, Jaffee EM, Ewend MG, Thomas MC, Tyler BM, Brem H. Thompson RC, et al. J Immunother Emphasis Tumor Immunol. 1996 Nov;19(6):405-13. doi: 10.1097/00002371-199611000-00004. J Immunother Emphasis Tumor Immunol. 1996. PMID: 9041459
Bioactivity of autologous irradiated renal cell carcinoma vaccines generated by ex vivo granulocyte-macrophage colony-stimulating factor gene transfer.
Simons JW, Jaffee EM, Weber CE, Levitsky HI, Nelson WG, Carducci MA, Lazenby AJ, Cohen LK, Finn CC, Clift SM, Hauda KM, Beck LA, Leiferman KM, Owens AH Jr, Piantadosi S, Dranoff G, Mulligan RC, Pardoll DM, Marshall FF. Simons JW, et al. Cancer Res. 1997 Apr 15;57(8):1537-46. Cancer Res. 1997. PMID: 9108457 Free PMC article. Clinical Trial.
Development and characterization of a cytokine-secreting pancreatic adenocarcinoma vaccine from primary tumors for use in clinical trials.
Jaffee EM, Schutte M, Gossett J, Morsberger LA, Adler AJ, Thomas M, Greten TF, Hruban RH, Yeo CJ, Griffin CA. Jaffee EM, et al. Cancer J Sci Am. 1998 May-Jun;4(3):194-203. Cancer J Sci Am. 1998. PMID: 9612602
Cancer vaccines.
Greten TF, Jaffee EM. Greten TF, et al. J Clin Oncol. 1999 Mar;17(3):1047-60. doi: 10.1200/JCO.1999.17.3.1047. J Clin Oncol. 1999. PMID: 10071300 Review.
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