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Page 1
Primary bovine embryonic fibroblasts demonstrate variable fitness following infection with highly pathogenic avian influenza H5N1 strains and are susceptible to a recently circulating human 2009 pandemic lineage H1N1 strain.
Wenger GK, Snyder DT, Prigge JR, Turner AH, Jaffrani SA, Schmidt EE, Bruce EA, Loveday EK. Wenger GK, et al. Among authors: jaffrani sa. Microbiol Spectr. 2026 Apr 7;14(4):e0328525. doi: 10.1128/spectrum.03285-25. Epub 2026 Feb 23. Microbiol Spectr. 2026. PMID: 41728991 Free PMC article.
Rab11B is required for binding and entry of recent H3N2, but not H1N1, influenza A isolates.
Turner AH, Jaffrani SA, Kubinski HC, Ajayi DP, Owens MB, Fanuele CD, McTigue MP, Appenzeller CL, Bowling A, Despres HW, Schmidt MM, Shirley DJ, Crothers JW, Barrantes-Reynolds R, Bruce EA. Turner AH, et al. Among authors: jaffrani sa. bioRxiv [Preprint]. 2025 Nov 18:2025.04.23.650275. doi: 10.1101/2025.04.23.650275. bioRxiv. 2025. Update in: J Virol. 2026 Jun 2:e0211125. doi: 10.1128/jvi.02111-25. PMID: 41332559 Free PMC article. Updated. Preprint.
Primary bovine embryonic fibroblasts support seasonal influenza A virus infection and demonstrate variable fitness of HPAI H5N1.
Wenger GK, Snyder DT, Prigge JR, Turner AH, Jaffrani SA, Schmidt EE, Bruce EA, Loveday EK. Wenger GK, et al. Among authors: jaffrani sa. bioRxiv [Preprint]. 2025 Jul 27:2025.07.26.666677. doi: 10.1101/2025.07.26.666677. bioRxiv. 2025. Update in: Microbiol Spectr. 2026 Apr 7;14(4):e0328525. doi: 10.1128/spectrum.03285-25. PMID: 40777344 Free PMC article. Updated. Preprint.
Variant mutation G215C in SARS-CoV-2 nucleocapsid enhances viral infection via altered genomic encapsidation.
Kubinski HC, Despres HW, Johnson BA, Schmidt MM, Jaffrani SA, Turner AH, Fanuele CD, Mills MG, Lokugamage KG, Dumas CM, Shirley DJ, Estes LK, Pekosz A, Crothers JW, Roychoudhury P, Greninger AL, Jerome KR, Di Genova BM, Walker DH, Ballif BA, Ladinsky MS, Bjorkman PJ, Menachery VD, Bruce EA. Kubinski HC, et al. Among authors: jaffrani sa. PLoS Biol. 2025 Apr 29;23(4):e3003115. doi: 10.1371/journal.pbio.3003115. eCollection 2025 Apr. PLoS Biol. 2025. PMID: 40299982 Free PMC article.
Variant mutation in SARS-CoV-2 nucleocapsid enhances viral infection via altered genomic encapsidation.
Kubinski HC, Despres HW, Johnson BA, Schmidt MM, Jaffrani SA, Mills MG, Lokugamage K, Dumas CM, Shirley DJ, Estes LK, Pekosz A, Crothers JW, Roychoudhury P, Greninger AL, Jerome KR, Di Genova BM, Walker DH, Ballif BA, Ladinsky MS, Bjorkman PJ, Menachery VD, Bruce EA. Kubinski HC, et al. Among authors: jaffrani sa. bioRxiv [Preprint]. 2024 Mar 11:2024.03.08.584120. doi: 10.1101/2024.03.08.584120. bioRxiv. 2024. Update in: PLoS Biol. 2025 Apr 29;23(4):e3003115. doi: 10.1371/journal.pbio.3003115. PMID: 38559000 Free PMC article. Updated. Preprint.