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Cellular mechanisms of insulin resistance: role of stress-regulated serine kinases and insulin receptor substrates (IRS) serine phosphorylation.
Tanti JF, Jager J. Tanti JF, et al. Among authors: jager j. Curr Opin Pharmacol. 2009 Dec;9(6):753-62. doi: 10.1016/j.coph.2009.07.004. Epub 2009 Aug 13. Curr Opin Pharmacol. 2009. PMID: 19683471 Review.
Interleukin-1beta-induced insulin resistance in adipocytes through down-regulation of insulin receptor substrate-1 expression.
Jager J, Grémeaux T, Cormont M, Le Marchand-Brustel Y, Tanti JF. Jager J, et al. Endocrinology. 2007 Jan;148(1):241-51. doi: 10.1210/en.2006-0692. Epub 2006 Oct 12. Endocrinology. 2007. PMID: 17038556 Free PMC article.
Involvement of TNF-alpha in abnormal adipocyte and muscle sortilin expression in obese mice and humans.
Kaddai V, Jager J, Gonzalez T, Najem-Lendom R, Bonnafous S, Tran A, Le Marchand-Brustel Y, Gual P, Tanti JF, Cormont M. Kaddai V, et al. Among authors: jager j. Diabetologia. 2009 May;52(5):932-40. doi: 10.1007/s00125-009-1273-3. Epub 2009 Feb 14. Diabetologia. 2009. PMID: 19219422
Tpl2 kinase is upregulated in adipose tissue in obesity and may mediate interleukin-1beta and tumor necrosis factor-{alpha} effects on extracellular signal-regulated kinase activation and lipolysis.
Jager J, Grémeaux T, Gonzalez T, Bonnafous S, Debard C, Laville M, Vidal H, Tran A, Gual P, Le Marchand-Brustel Y, Cormont M, Tanti JF. Jager J, et al. Diabetes. 2010 Jan;59(1):61-70. doi: 10.2337/db09-0470. Epub 2009 Oct 6. Diabetes. 2010. PMID: 19808894 Free PMC article.
Apelin and APJ regulation in adipose tissue and skeletal muscle of type 2 diabetic mice and humans.
Dray C, Debard C, Jager J, Disse E, Daviaud D, Martin P, Attané C, Wanecq E, Guigné C, Bost F, Tanti JF, Laville M, Vidal H, Valet P, Castan-Laurell I. Dray C, et al. Among authors: jager j. Am J Physiol Endocrinol Metab. 2010 Jun;298(6):E1161-9. doi: 10.1152/ajpendo.00598.2009. Epub 2010 Mar 16. Am J Physiol Endocrinol Metab. 2010. PMID: 20233941
Deficiency in the extracellular signal-regulated kinase 1 (ERK1) protects leptin-deficient mice from insulin resistance without affecting obesity.
Jager J, Corcelle V, Grémeaux T, Laurent K, Waget A, Pagès G, Binétruy B, Le Marchand-Brustel Y, Burcelin R, Bost F, Tanti JF. Jager J, et al. Diabetologia. 2011 Jan;54(1):180-9. doi: 10.1007/s00125-010-1944-0. Epub 2010 Oct 15. Diabetologia. 2011. PMID: 20953578
Implication of inflammatory signaling pathways in obesity-induced insulin resistance.
Tanti JF, Ceppo F, Jager J, Berthou F. Tanti JF, et al. Among authors: jager j. Front Endocrinol (Lausanne). 2013 Jan 8;3:181. doi: 10.3389/fendo.2012.00181. eCollection 2012. Front Endocrinol (Lausanne). 2013. PMID: 23316186 Free PMC article.
Implication of the Tpl2 kinase in inflammatory changes and insulin resistance induced by the interaction between adipocytes and macrophages.
Ceppo F, Berthou F, Jager J, Dumas K, Cormont M, Tanti JF. Ceppo F, et al. Among authors: jager j. Endocrinology. 2014 Mar;155(3):951-64. doi: 10.1210/en.2013-1815. Epub 2014 Jan 1. Endocrinology. 2014. PMID: 24424060
[Implication of MAP kinases in obesity-induced inflammation and insulin resistance].
Ceppo F, Jager J, Berthou F, Giorgetti-Peraldi S, Cormont M, Bost F, Tanti JF. Ceppo F, et al. Among authors: jager j. Biol Aujourdhui. 2014;208(2):97-107. doi: 10.1051/jbio/2014014. Epub 2014 Sep 8. Biol Aujourdhui. 2014. PMID: 25190570 Review. French.
p38MAP Kinase activity is required for human primary adipocyte differentiation.
Aouadi M, Jager J, Laurent K, Gonzalez T, Cormont M, Binétruy B, Le Marchand-Brustel Y, Tanti JF, Bost F. Aouadi M, et al. Among authors: jager j. FEBS Lett. 2007 Dec 11;581(29):5591-6. doi: 10.1016/j.febslet.2007.10.064. Epub 2007 Nov 13. FEBS Lett. 2007. PMID: 17997987
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