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A bioinspired omniphobic surface coating on medical devices prevents thrombosis and biofouling.
Leslie DC, Waterhouse A, Berthet JB, Valentin TM, Watters AL, Jain A, Kim P, Hatton BD, Nedder A, Donovan K, Super EH, Howell C, Johnson CP, Vu TL, Bolgen DE, Rifai S, Hansen AR, Aizenberg M, Super M, Aizenberg J, Ingber DE. Leslie DC, et al. Among authors: jain a. Nat Biotechnol. 2014 Nov;32(11):1134-40. doi: 10.1038/nbt.3020. Epub 2014 Oct 12. Nat Biotechnol. 2014. PMID: 25306244
Engineered in vitro disease models.
Benam KH, Dauth S, Hassell B, Herland A, Jain A, Jang KJ, Karalis K, Kim HJ, MacQueen L, Mahmoodian R, Musah S, Torisawa YS, van der Meer AD, Villenave R, Yadid M, Parker KK, Ingber DE. Benam KH, et al. Among authors: jain a. Annu Rev Pathol. 2015;10:195-262. doi: 10.1146/annurev-pathol-012414-040418. Annu Rev Pathol. 2015. PMID: 25621660 Review.
PAR1 agonists stimulate APC-like endothelial cytoprotection and confer resistance to thromboinflammatory injury.
De Ceunynck K, Peters CG, Jain A, Higgins SJ, Aisiku O, Fitch-Tewfik JL, Chaudhry SA, Dockendorff C, Parikh SM, Ingber DE, Flaumenhaft R. De Ceunynck K, et al. Among authors: jain a. Proc Natl Acad Sci U S A. 2018 Jan 30;115(5):E982-E991. doi: 10.1073/pnas.1718600115. Epub 2018 Jan 17. Proc Natl Acad Sci U S A. 2018. PMID: 29343648 Free PMC article.
Organ-on-Chip Recapitulates Thrombosis Induced by an anti-CD154 Monoclonal Antibody: Translational Potential of Advanced Microengineered Systems.
Barrile R, van der Meer AD, Park H, Fraser JP, Simic D, Teng F, Conegliano D, Nguyen J, Jain A, Zhou M, Karalis K, Ingber DE, Hamilton GA, Otieno MA. Barrile R, et al. Among authors: jain a. Clin Pharmacol Ther. 2018 Dec;104(6):1240-1248. doi: 10.1002/cpt.1054. Epub 2018 Apr 30. Clin Pharmacol Ther. 2018. PMID: 29484632
8,636 results