Jaini R - Search Results

1

Cross-level analysis of molecular and neurobehavioral function in a prospective series of patients with germline heterozygous PTEN mutations with and without autism.

Frazier TW, Jaini R, Busch RM, Wolf M, Sadler T, Klaas P, Hardan AY, Martinez-Agosto JA, Sahin M, Eng C; Developmental Synaptopathies Consortium. Frazier TW, et al. Among authors: jaini r. Mol Autism. 2021 Jan 28;12(1):5. doi: 10.1186/s13229-020-00406-6. Mol Autism. 2021. PMID: 33509259 Free PMC article.

2

Dynamics and structural stability effects of germline PTEN mutations associated with cancer versus autism phenotypes.

Smith IN, Thacker S, Jaini R, Eng C. Smith IN, et al. Among authors: jaini r. J Biomol Struct Dyn. 2019 Apr;37(7):1766-1782. doi: 10.1080/07391102.2018.1465854. Epub 2018 May 14. J Biomol Struct Dyn. 2019. PMID: 29663862 Free PMC article.

3

Maternal genetics influences fetal neurodevelopment and postnatal autism spectrum disorder-like phenotype by modulating in-utero immunosuppression.

Jaini R, Wolf MR, Yu Q, King AT, Frazier TW Jr, Eng C. Jaini R, et al. Transl Psychiatry. 2021 Jun 5;11(1):348. doi: 10.1038/s41398-021-01472-x. Transl Psychiatry. 2021. PMID: 34091589 Free PMC article.

4

Decreased nuclear Pten in neural stem cells contributes to deficits in neuronal maturation.

Kang SC, Jaini R, Hitomi M, Lee H, Sarn N, Thacker S, Eng C. Kang SC, et al. Among authors: jaini r. Mol Autism. 2020 Jun 1;11(1):43. doi: 10.1186/s13229-020-00337-2. Mol Autism. 2020. PMID: 32487265 Free PMC article.

5

Cytoplasmic-predominant Pten increases microglial activation and synaptic pruning in a murine model with autism-like phenotype.

Sarn N, Jaini R, Thacker S, Lee H, Dutta R, Eng C. Sarn N, et al. Among authors: jaini r. Mol Psychiatry. 2021 May;26(5):1458-1471. doi: 10.1038/s41380-020-0681-0. Epub 2020 Feb 13. Mol Psychiatry. 2021. PMID: 32055008 Free PMC article.

6

Germline PTEN mutations are associated with a skewed peripheral immune repertoire in humans and mice.

Jaini R, Loya MG, King AT, Thacker S, Sarn NB, Yu Q, Stark GR, Eng C. Jaini R, et al. Hum Mol Genet. 2020 Aug 11;29(14):2353-2364. doi: 10.1093/hmg/ddaa118. Hum Mol Genet. 2020. PMID: 32588888 Free PMC article.

7

Redefining the PTEN promoter: identification of novel upstream transcription start regions.

Grencewicz DJ, Romigh T, Thacker S, Abbas A, Jaini R, Luse D, Eng C. Grencewicz DJ, et al. Among authors: jaini r. Hum Mol Genet. 2021 Nov 1;30(22):2135-2148. doi: 10.1093/hmg/ddab175. Hum Mol Genet. 2021. PMID: 34218272

8

Cowden syndrome-associated germline succinate dehydrogenase complex subunit D (SDHD) variants cause PTEN-mediated down-regulation of autophagy in thyroid cancer cells.

Yu W, Ni Y, Saji M, Ringel MD, Jaini R, Eng C. Yu W, et al. Among authors: jaini r. Hum Mol Genet. 2017 Apr 1;26(7):1365-1375. doi: 10.1093/hmg/ddx037. Hum Mol Genet. 2017. PMID: 28164237 Free PMC article.

9

Immunotherapeutic target expression on breast tumors can be amplified by hormone receptor antagonism: a novel strategy for enhancing efficacy of targeted immunotherapy.

Jaini R, Loya MG, Eng C. Jaini R, et al. Oncotarget. 2017 May 16;8(20):32536-32549. doi: 10.18632/oncotarget.15812. Oncotarget. 2017. PMID: 28430646 Free PMC article.

10

Disruption of estrous cycle homeostasis in mice with experimental autoimmune encephalomyelitis.

Jaini R, Altuntas CZ, Loya MG, Tuohy VK. Jaini R, et al. J Neuroimmunol. 2015 Feb 15;279:71-4. doi: 10.1016/j.jneuroim.2015.01.002. Epub 2015 Jan 10. J Neuroimmunol. 2015. PMID: 25670003

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