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Alpha-synuclein in Lewy bodies.
Spillantini MG, Schmidt ML, Lee VM, Trojanowski JQ, Jakes R, Goedert M. Spillantini MG, et al. Among authors: jakes r. Nature. 1997 Aug 28;388(6645):839-40. doi: 10.1038/42166. Nature. 1997. PMID: 9278044 No abstract available.
Early-onset dementia with Lewy bodies.
Takao M, Ghetti B, Yoshida H, Piccardo P, Narain Y, Murrell JR, Vidal R, Glazier BS, Jakes R, Tsutsui M, Spillantini MG, Crowther RA, Goedert M, Koto A. Takao M, et al. Among authors: jakes r. Brain Pathol. 2004 Apr;14(2):137-47. doi: 10.1111/j.1750-3639.2004.tb00046.x. Brain Pathol. 2004. PMID: 15193026
Lewy body variant of Alzheimer's disease: selective neocortical loss of t-SNARE proteins and loss of MAP2 and alpha-synuclein in medial temporal lobe.
Mukaetova-Ladinska EB, Xuereb JH, Garcia-Sierra F, Hurt J, Gertz HJ, Hills R, Brayne C, Huppert FA, Paykel ES, McGee MA, Jakes R, Honer WG, Harrington CR, Wischik CM. Mukaetova-Ladinska EB, et al. Among authors: jakes r. ScientificWorldJournal. 2009 Dec 16;9:1463-75. doi: 10.1100/tsw.2009.151. ScientificWorldJournal. 2009. PMID: 20024519 Free PMC article.
Mutation E46K increases phospholipid binding and assembly into filaments of human alpha-synuclein.
Choi W, Zibaee S, Jakes R, Serpell LC, Davletov B, Crowther RA, Goedert M. Choi W, et al. Among authors: jakes r. FEBS Lett. 2004 Oct 22;576(3):363-8. doi: 10.1016/j.febslet.2004.09.038. FEBS Lett. 2004. PMID: 15498564
Intraneuronal filamentous tau protein and alpha-synuclein deposits in neurodegenerative diseases.
Goedert M, Jakes R, Crowther RA, Hasegawa M, Smith MJ, Spillantini MG. Goedert M, et al. Among authors: jakes r. Biochem Soc Trans. 1998 Aug;26(3):463-71. doi: 10.1042/bst0260463. Biochem Soc Trans. 1998. PMID: 9765897 Review. No abstract available.
From genetics to pathology: tau and alpha-synuclein assemblies in neurodegenerative diseases.
Goedert M, Spillantini MG, Serpell LC, Berriman J, Smith MJ, Jakes R, Crowther RA. Goedert M, et al. Among authors: jakes r. Philos Trans R Soc Lond B Biol Sci. 2001 Feb 28;356(1406):213-27. doi: 10.1098/rstb.2000.0767. Philos Trans R Soc Lond B Biol Sci. 2001. PMID: 11260802 Free PMC article. Review.
Filamentous alpha-synuclein inclusions link multiple system atrophy with Parkinson's disease and dementia with Lewy bodies.
Spillantini MG, Crowther RA, Jakes R, Cairns NJ, Lantos PL, Goedert M. Spillantini MG, et al. Among authors: jakes r. Neurosci Lett. 1998 Jul 31;251(3):205-8. doi: 10.1016/s0304-3940(98)00504-7. Neurosci Lett. 1998. PMID: 9726379
Binding of alpha-synuclein to brain vesicles is abolished by familial Parkinson's disease mutation.
Jensen PH, Nielsen MS, Jakes R, Dotti CG, Goedert M. Jensen PH, et al. Among authors: jakes r. J Biol Chem. 1998 Oct 9;273(41):26292-4. doi: 10.1074/jbc.273.41.26292. J Biol Chem. 1998. PMID: 9756856
Alpha-synuclein inclusions in Alzheimer and Lewy body diseases.
Mukaetova-Ladinska EB, Hurt J, Jakes R, Xuereb J, Honer WG, Wischik CM. Mukaetova-Ladinska EB, et al. Among authors: jakes r. J Neuropathol Exp Neurol. 2000 May;59(5):408-17. doi: 10.1093/jnen/59.5.408. J Neuropathol Exp Neurol. 2000. PMID: 10888371
Epitope mapping of LB509, a monoclonal antibody directed against human alpha-synuclein.
Jakes R, Crowther RA, Lee VM, Trojanowski JQ, Iwatsubo T, Goedert M. Jakes R, et al. Neurosci Lett. 1999 Jul 2;269(1):13-6. doi: 10.1016/s0304-3940(99)00411-5. Neurosci Lett. 1999. PMID: 10821633
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