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Intracerebral hemorrhage location and outcome among INTERACT2 participants.
Delcourt C, Sato S, Zhang S, Sandset EC, Zheng D, Chen X, Hackett ML, Arima H, Hata J, Heeley E, Al-Shahi Salman R, Robinson T, Davies L, Lavados PM, Lindley RI, Stapf C, Chalmers J, Anderson CS; INTERACT2 Investigators. Delcourt C, et al. Neurology. 2017 Apr 11;88(15):1408-1414. doi: 10.1212/WNL.0000000000003771. Epub 2017 Feb 24. Neurology. 2017. PMID: 28235817 Free PMC article. Clinical Trial.
Involvement of the posterior limb of the internal capsule, thalamus, and infratentorial sites were each associated with poor EQ-5D utility score (0.7 [median]; OR 1.87, 2.14, and 2.81, respectively). ...The highest association with death or major disability and poor EQ- …
Involvement of the posterior limb of the internal capsule, thalamus, and infratentorial sites were each associated with poor EQ-5D ut …
Comparison of cytokine and phosphoprotein profiles in idiopathic and Crohn's disease-related perianal fistula.
Haddow JB, Musbahi O, MacDonald TT, Knowles CH. Haddow JB, et al. World J Gastrointest Pathophysiol. 2019 Nov 13;10(4):42-53. doi: 10.4291/wjgp.v10.i4.42. World J Gastrointest Pathophysiol. 2019. PMID: 31750007 Free PMC article.
AIM: To systematically compare the clinical phenotypes, cytokine and phosphoprotein profiles of idiopathic and CD-related perianal fistulae. METHODS: Sixty-one patients undergoing surgery for perianal fistula were prospectively recruited (48 idiopathic, 13 CD) into …
AIM: To systematically compare the clinical phenotypes, cytokine and phosphoprotein profiles of idiopathic and CD-related perianal fi …
Health-economic analysis: cost-effectiveness of scheduled maintenance treatment with infliximab for Crohn's disease--modelling outcomes in active luminal and fistulizing disease in adults.
Lindsay J, Punekar YS, Morris J, Chung-Faye G. Lindsay J, et al. Aliment Pharmacol Ther. 2008 Jul;28(1):76-87. doi: 10.1111/j.1365-2036.2008.03709.x. Epub 2008 Apr 11. Aliment Pharmacol Ther. 2008. PMID: 18410558 Free article.
BACKGROUND: Infliximab has been shown to be efficacious in moderate-to-severe Crohn's disease (CD). AIM: To evaluate the cost-effectiveness of scheduled maintenance treatment with infliximab in luminal and fistulizing CD patients. ...RESULTS: The incremental cost pe …
BACKGROUND: Infliximab has been shown to be efficacious in moderate-to-severe Crohn's disease (CD). AIM: To evaluate the cost-effecti …
The solution structures of higher-order human telomere G-quadruplex multimers.
Monsen RC, Chakravarthy S, Dean WL, Chaires JB, Trent JO. Monsen RC, et al. Nucleic Acids Res. 2021 Feb 22;49(3):1749-1768. doi: 10.1093/nar/gkaa1285. Nucleic Acids Res. 2021. PMID: 33469644 Free PMC article.
We report here the results of an integrated structural biology approach that combines small-angle X-ray scattering, circular dichroism (CD), analytical ultracentrifugation, size-exclusion column chromatography and molecular dynamics simulations that provide the most detail …
We report here the results of an integrated structural biology approach that combines small-angle X-ray scattering, circular dichroism (C
The carcinogenicity of discontinuous inhaled benzene exposures in CD-1 and C57Bl/6 mice.
Snyder CA, Sellakumar AR, James DJ, Albert RE. Snyder CA, et al. Arch Toxicol. 1988;62(5):331-5. doi: 10.1007/BF00293618. Arch Toxicol. 1988. PMID: 3242441
Groups of male C57Bl and CD-1 mice were exposed to benzene via inhalation using two different exposure protocols. ...Particularly noteworthy was a 35% incidence of zymbal gland tumors in the C57Bl mice. In contrast, only the CD-1 mice responded to the 1200 ppm benze …
Groups of male C57Bl and CD-1 mice were exposed to benzene via inhalation using two different exposure protocols. ...Particularly not …