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Association Between Body Mass Index and Functional Outcomes in Patients With Intracerebral Hemorrhage.
Becerril-Gaitan A, Ding D, Ironside N, Southerland AM, Worrall BB, Testai FD, Flaherty ML, Elkind MS, Koch S, Sung G, Kittner SJ, Mayson DJ, Gonzales N, McCauley JL, Malkoff M, Hall CE, Frankel MR, James ML, Anderson CD, Aronowski J, Savitz SI, Woo D, Chen CJ; ERICH investigators. Becerril-Gaitan A, et al. Neurology. 2024 Jan 23;102(2):e208014. doi: 10.1212/WNL.0000000000208014. Epub 2023 Dec 21. Neurology. 2024. PMID: 38165334 Free PMC article.
Compared with patients with BMI <25 kg/m(2), those with BMI 25 kg/m(2) had better 90-day mRS (aOR = 0.80 [CI 0.67-0.95]), EuroQoL Group 5-Dimension (EQ-5D) (abeta = 0.05 [0.01-0.08]), and EQ-5D VAS (abeta = 3.80 [0.80-6.98]) scores. These differences persisted af …
Compared with patients with BMI <25 kg/m(2), those with BMI 25 kg/m(2) had better 90-day mRS (aOR = 0.80 [CI 0.67-0.95]), EuroQoL Group 5 …
The solution structures of higher-order human telomere G-quadruplex multimers.
Monsen RC, Chakravarthy S, Dean WL, Chaires JB, Trent JO. Monsen RC, et al. Nucleic Acids Res. 2021 Feb 22;49(3):1749-1768. doi: 10.1093/nar/gkaa1285. Nucleic Acids Res. 2021. PMID: 33469644 Free PMC article.
We report here the results of an integrated structural biology approach that combines small-angle X-ray scattering, circular dichroism (CD), analytical ultracentrifugation, size-exclusion column chromatography and molecular dynamics simulations that provide the most detail …
We report here the results of an integrated structural biology approach that combines small-angle X-ray scattering, circular dichroism (C …
Intracerebral hemorrhage location and outcome among INTERACT2 participants.
Delcourt C, Sato S, Zhang S, Sandset EC, Zheng D, Chen X, Hackett ML, Arima H, Hata J, Heeley E, Al-Shahi Salman R, Robinson T, Davies L, Lavados PM, Lindley RI, Stapf C, Chalmers J, Anderson CS; INTERACT2 Investigators. Delcourt C, et al. Neurology. 2017 Apr 11;88(15):1408-1414. doi: 10.1212/WNL.0000000000003771. Epub 2017 Feb 24. Neurology. 2017. PMID: 28235817 Free PMC article. Clinical Trial.
Involvement of the posterior limb of the internal capsule, thalamus, and infratentorial sites were each associated with poor EQ-5D utility score (0.7 [median]; OR 1.87, 2.14, and 2.81, respectively). Posterior limb of internal capsule involvement was strongly associated wi …
Involvement of the posterior limb of the internal capsule, thalamus, and infratentorial sites were each associated with poor EQ-5D ut …
Comparison of cytokine and phosphoprotein profiles in idiopathic and Crohn's disease-related perianal fistula.
Haddow JB, Musbahi O, MacDonald TT, Knowles CH. Haddow JB, et al. World J Gastrointest Pathophysiol. 2019 Nov 13;10(4):42-53. doi: 10.4291/wjgp.v10.i4.42. World J Gastrointest Pathophysiol. 2019. PMID: 31750007 Free PMC article.
BACKGROUND: Perianal fistulae are either primary (idiopathic) or secondary [commonly associated with Crohn's disease, (CD)]. It is assumed, although not proven, that the pathophysiology differs. AIM: To systematically compare the clinical phenotypes, cytokine and phosphopr …
BACKGROUND: Perianal fistulae are either primary (idiopathic) or secondary [commonly associated with Crohn's disease, (CD)]. It is as …
The prevalence of Fabry disease in a statewide chronic kidney disease cohort - Outcomes of the aCQuiRE (Ckd.Qld fabRy Epidemiology) study.
Mallett A, Kearey PJ, Cameron A, Healy HG, Denaro C, Thomas M, Lee VW, Stark SL, Fuller M, Wang Z, Hoy WE. Mallett A, et al. BMC Nephrol. 2022 May 4;23(1):169. doi: 10.1186/s12882-022-02805-8. BMC Nephrol. 2022. PMID: 35505287 Free PMC article.
METHODS: We undertook a cross-sectional study employing a cascade screening strategy for Fabry Disease amongst 3000 adult, male and female patients affected by CKD stage 1-5D/T at public, specialty renal practices within participating Queensland Hospital and Health Service …
METHODS: We undertook a cross-sectional study employing a cascade screening strategy for Fabry Disease amongst 3000 adult, male and female p …
Validation of the European Oncology toolkit for the self-assessment of Quality of Life (EUonQoL-Kit) in cancer patients and survivors: study protocol of a pan European survey.
Apolone G, Costantini M, Caselli L, Bos N, Caraceni A, Ciliberto G, Couespel N, Ferrer M, Groenvold M, Kaasa S, Lombardo C, Pietrobon R, Pravettoni G, Sirven A, Vachon H, Velikova G, Garin O, Gilbert A, Machiavelli A, Marzorati C, Miceli R, Pe M, Petersen MA, Tanzilli A, van Schelven F, Dantas C, Minnée-van Braak I, Pinnavaia L, Brunelli C. Apolone G, et al. BMC Public Health. 2024 Dec 18;24(1):3517. doi: 10.1186/s12889-024-21008-4. BMC Public Health. 2024. PMID: 39696103 Free PMC article.
All participants will complete the static EUonQoL-Kit; three subsamples (each 10% of the total sample) will also respectively complete the following: a) dynamic EUonQoL-Kit, based on Item Response Theory (IRT)/Computer Adaptive Testing (CAT), b) FACT-G and EQ-5L-5D, and c) …
All participants will complete the static EUonQoL-Kit; three subsamples (each 10% of the total sample) will also respectively complete the f …
Health-economic analysis: cost-effectiveness of scheduled maintenance treatment with infliximab for Crohn's disease--modelling outcomes in active luminal and fistulizing disease in adults.
Lindsay J, Punekar YS, Morris J, Chung-Faye G. Lindsay J, et al. Aliment Pharmacol Ther. 2008 Jul;28(1):76-87. doi: 10.1111/j.1365-2036.2008.03709.x. Epub 2008 Apr 11. Aliment Pharmacol Ther. 2008. PMID: 18410558
BACKGROUND: Infliximab has been shown to be efficacious in moderate-to-severe Crohn's disease (CD). AIM: To evaluate the cost-effectiveness of scheduled maintenance treatment with infliximab in luminal and fistulizing CD patients. ...RESULTS: The incremental cost pe …
BACKGROUND: Infliximab has been shown to be efficacious in moderate-to-severe Crohn's disease (CD). AIM: To evaluate the cost-effecti …
The carcinogenicity of discontinuous inhaled benzene exposures in CD-1 and C57Bl/6 mice.
Snyder CA, Sellakumar AR, James DJ, Albert RE. Snyder CA, et al. Arch Toxicol. 1988;62(5):331-5. doi: 10.1007/BF00293618. Arch Toxicol. 1988. PMID: 3242441
Groups of male C57Bl and CD-1 mice were exposed to benzene via inhalation using two different exposure protocols. ...Particularly noteworthy was a 35% incidence of zymbal gland tumors in the C57Bl mice. In contrast, only the CD-1 mice responded to the 1200 ppm benze …
Groups of male C57Bl and CD-1 mice were exposed to benzene via inhalation using two different exposure protocols. ...Particularly not …