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The T cell receptor triggering apparatus is composed of monovalent or monomeric proteins.
James JR, McColl J, Oliveira MI, Dunne PD, Huang E, Jansson A, Nilsson P, Sleep DL, Gonçalves CM, Morgan SH, Felce JH, Mahen R, Fernandes RA, Carmo AM, Klenerman D, Davis SJ. James JR, et al. J Biol Chem. 2011 Sep 16;286(37):31993-2001. doi: 10.1074/jbc.M111.219212. Epub 2011 Jul 13. J Biol Chem. 2011. PMID: 21757710 Free PMC article.
The platelet receptor CLEC-2 is active as a dimer.
Watson AA, Christou CM, James JR, Fenton-May AE, Moncayo GE, Mistry AR, Davis SJ, Gilbert RJ, Chakera A, O'Callaghan CA. Watson AA, et al. Among authors: james jr. Biochemistry. 2009 Nov 24;48(46):10988-96. doi: 10.1021/bi901427d. Biochemistry. 2009. PMID: 19824697
Crystal structure of a soluble CD28-Fab complex.
Evans EJ, Esnouf RM, Manso-Sancho R, Gilbert RJ, James JR, Yu C, Fennelly JA, Vowles C, Hanke T, Walse B, Hünig T, Sørensen P, Stuart DI, Davis SJ. Evans EJ, et al. Among authors: james jr. Nat Immunol. 2005 Mar;6(3):271-9. doi: 10.1038/ni1170. Epub 2005 Feb 6. Nat Immunol. 2005. PMID: 15696168
Glycoprotein VI oligomerization in cell lines and platelets.
Berlanga O, Bori-Sanz T, James JR, Frampton J, Davis SJ, Tomlinson MG, Watson SP. Berlanga O, et al. Among authors: james jr. J Thromb Haemost. 2007 May;5(5):1026-1033. doi: 10.1111/j.1538-7836.2007.02449.x. Epub 2007 Mar 15. J Thromb Haemost. 2007. PMID: 17367493 Free PMC article.
Ferroportin: lack of evidence for multimers.
Schimanski LM, Drakesmith H, Talbott C, Horne K, James JR, Davis SJ, Sweetland E, Bastin J, Cowley D, Townsend AR. Schimanski LM, et al. Among authors: james jr. Blood Cells Mol Dis. 2008 May-Jun;40(3):360-9. doi: 10.1016/j.bcmd.2007.09.007. Epub 2007 Oct 31. Blood Cells Mol Dis. 2008. PMID: 17977032
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