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A peroxisome proliferator-activated receptor-alpha (PPARalpha) cDNA cloned from guinea-pig liver encodes a protein with similar properties to the mouse PPARalpha: implications for species differences in responses to peroxisome proliferators.
Tugwood JD, Holden PR, James NH, Prince RA, Roberts RA. Tugwood JD, et al. Among authors: james nh. Arch Toxicol. 1998 Feb;72(3):169-77. doi: 10.1007/s002040050483. Arch Toxicol. 1998. PMID: 9520140
Downregulation of lactoferrin by PPARalpha ligands: role in perturbation of hepatocyte proliferation and apoptosis.
Hasmall S, Orphanides G, James N, Pennie W, Hedley K, Soames A, Kimber I, Roberts R. Hasmall S, et al. Among authors: james n. Toxicol Sci. 2002 Aug;68(2):304-13. doi: 10.1093/toxsci/68.2.304. Toxicol Sci. 2002. PMID: 12151626
Role of MAP kinase signalling pathways in the mode of action of peroxisome proliferators.
Cosulich S, James N, Roberts R. Cosulich S, et al. Among authors: james n. Carcinogenesis. 2000 Apr;21(4):579-84. doi: 10.1093/carcin/21.4.579. Carcinogenesis. 2000. PMID: 10753189
Mouse hepatocyte response to peroxisome proliferators: dependency on hepatic nonparenchymal cells and peroxisome proliferator activated receptor alpha (PPARalpha).
Hasmall S, James N, Hedley K, Olsen K, Roberts R. Hasmall S, et al. Among authors: james n. Arch Toxicol. 2001 Aug;75(6):357-61. doi: 10.1007/s002040100246. Arch Toxicol. 2001. PMID: 11570693
The peroxisome proliferator nafenopin does not suppress hepatocyte apoptosis in guinea-pig liver in vivo nor in human hepatocytes in vitro.
Hasmall SC, James NH, Soames AR, Roberts RA. Hasmall SC, et al. Among authors: james nh. Arch Toxicol. 1998 Dec;72(12):777-83. doi: 10.1007/s002040050573. Arch Toxicol. 1998. PMID: 9950074
PPAR alpha and the regulation of cell division and apoptosis.
Roberts RA, Chevalier S, Hasmall SC, James NH, Cosulich SC, Macdonald N. Roberts RA, et al. Among authors: james nh. Toxicology. 2002 Dec 27;181-182:167-70. doi: 10.1016/s0300-483x(02)00275-5. Toxicology. 2002. PMID: 12505304 Review.
Role of cytokines in non-genotoxic hepatocarcinogenesis: cause or effect?
Roberts RA, James NH, Cosulich S, Hasmall SC, Orphanides G. Roberts RA, et al. Among authors: james nh. Toxicol Lett. 2001 Mar 31;120(1-3):301-6. doi: 10.1016/s0378-4274(01)00282-x. Toxicol Lett. 2001. PMID: 11323188 Review.
Identification of a possible association between carbon tetrachloride-induced hepatotoxicity and interleukin-8 expression.
Holden PR, James NH, Brooks AN, Roberts RA, Kimber I, Pennie WD. Holden PR, et al. Among authors: james nh. J Biochem Mol Toxicol. 2000;14(5):283-90. doi: 10.1002/1099-0461(2000)14:5<283::AID-JBT7>3.0.CO;2-S. J Biochem Mol Toxicol. 2000. PMID: 10970000
A dominant negative form of IKK2 prevents suppression of apoptosis by the peroxisome proliferator nafenopin.
Cosulich SC, James NH, Needham MR, Newham PP, Bundell KR, Roberts RA. Cosulich SC, et al. Among authors: james nh. Carcinogenesis. 2000 Sep;21(9):1757-60. doi: 10.1093/carcin/21.9.1757. Carcinogenesis. 2000. PMID: 10964109
Species differences in response to diethylhexylphthalate: suppression of apoptosis, induction of DNA synthesis and peroxisome proliferator activated receptor alpha-mediated gene expression.
Hasmall SC, James NH, Macdonald N, Soames AR, Roberts RA. Hasmall SC, et al. Among authors: james nh. Arch Toxicol. 2000 Apr;74(2):85-91. doi: 10.1007/s002040050657. Arch Toxicol. 2000. PMID: 10839475
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