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Determinants of progression to cirrhosis or fibrosis in pure alcoholic fatty liver.
Teli MR, Day CP, Burt AD, Bennett MK, James OF. Teli MR, et al. Among authors: james of. Lancet. 1995 Oct 14;346(8981):987-90. doi: 10.1016/s0140-6736(95)91685-7. Lancet. 1995. PMID: 7475591
We have followed 88 patients, first seen between 1978 and 1985, with a histological diagnosis of pure alcoholic fatty liver and no evidence of fibrosis or alcoholic hepatitis, for a median of 10.5 years, to determine any factors predictive of disease p …
We have followed 88 patients, first seen between 1978 and 1985, with a histological diagnosis of pure alcoholic fatty liver and no ev …
Alcohol consumption and dependence in elderly patients in an urban community.
Bridgewater R, Leigh S, James OF, Potter JF. Bridgewater R, et al. Among authors: james of. Br Med J (Clin Res Ed). 1987 Oct 10;295(6603):884-5. doi: 10.1136/bmj.295.6603.884. Br Med J (Clin Res Ed). 1987. PMID: 3119085 Free PMC article. No abstract available.
Alcoholic liver disease in Scotland and northeastern England: presenting features in 510 patients.
Hislop WS, Bouchier IA, Allan JG, Brunt PW, Eastwood M, Finlayson ND, James O, Russell RI, Watkinson G. Hislop WS, et al. Among authors: james o. Q J Med. 1983 Spring;52(206):232-43. Q J Med. 1983. PMID: 6604294
A study of 510 patients in Scotland and northeastern England with histological evidence of alcohol-induced liver disease showed no difference in the age of presentation between males and females. ...Gastro-oesophageal varices accounted for 40% of insta …
A study of 510 patients in Scotland and northeastern England with histological evidence of alcohol-induced liver disease showe …
Primary biliary cirrhosis: identification of two major M2 mitochondrial autoantigens.
Yeaman SJ, Fussey SP, Danner DJ, James OF, Mutimer DJ, Bassendine MF. Yeaman SJ, et al. Among authors: james of. Lancet. 1988 May 14;1(8594):1067-70. doi: 10.1016/s0140-6736(88)91894-6. Lancet. 1988. PMID: 2896910
Immunoblotting showed that a second subunit of the pyruvate dehydrogenase complex, a 50 kD polypeptide of unknown function (component X), is also an M2 autoantigen. Identification of these M2 mitochondrial antigens should facilitate the development of
Immunoblotting showed that a second subunit of the pyruvate dehydrogenase complex, a 50 kD polypeptide of unknown function (co …
The effect of alcoholic cirrhosis on the two kinetic components (high and low affinity) of the microsomal 0-deethylation of 7-ethoxycoumarin in human liver.
Woodhouse KW, Williams FM, Mutch E, Wright P, James OF, Rawlins MD. Woodhouse KW, et al. Among authors: james of. Eur J Clin Pharmacol. 1984;26(1):61-4. doi: 10.1007/BF00546710. Eur J Clin Pharmacol. 1984. PMID: 6609077
The activities of the two kinetic components (high and low affinity) of the microsomal 0-deethylation of 7-ethoxycoumarin have been measured in liver from patients with alcoholic cirrhosis and in normals. The activity (expressed as pmol 7-OH coumarin formed/m …
The activities of the two kinetic components (high and low affinity) of the microsomal 0-deethylation of 7-ethoxycoumar …
The acute and subchronic effects of ketoconazole on hepatic microsomal monooxygenases in the rat.
Thomson RG, Rawlins MD, James OF, Wood P, Williams FM. Thomson RG, et al. Among authors: james of. Biochem Pharmacol. 1988 Oct 15;37(20):3975-80. doi: 10.1016/0006-2952(88)90082-2. Biochem Pharmacol. 1988. PMID: 3190741
Female adult Wistar rats were treated with single or repeated doses of ketoconazole ranging from 10 mg/kg to 100 mg/kg. Single dose treatment produced inhibition of hepatic microsomal ethoxyresorufin O-deethylation (EROD) and aldrin epoxidation (AE) 2 hr after oral …
Female adult Wistar rats were treated with single or repeated doses of ketoconazole ranging from 10 mg/kg to 100 mg/kg. Single dose t …
Letter: Endoscopic liver biopsy.
Roberts SH, James OF. Roberts SH, et al. Among authors: james of. Lancet. 1974 Dec 7;2(7893):1395. doi: 10.1016/s0140-6736(74)92275-2. Lancet. 1974. PMID: 4143361 No abstract available.
Osteoporosis in primary biliary cirrhosis revisited.
Newton J, Francis R, Prince M, James O, Bassendine M, Rawlings D, Jones D. Newton J, et al. Among authors: james o. Gut. 2001 Aug;49(2):282-7. doi: 10.1136/gut.49.2.282. Gut. 2001. PMID: 11454807 Free PMC article.
DESIGN: Retrospective review of a large cohort of well characterised PBC patients. PATIENTS: A total of 272 PBC patients with definite or probable PBC followed up for a mean of 10.1 years (total follow up 2726 patient years) who had at least one bone m …
DESIGN: Retrospective review of a large cohort of well characterised PBC patients. PATIENTS: A total of 272 PBC patient …
Incidence and prognostic importance of jaundice after cardiopulmonary bypass surgery.
Collins JD, Bassendine MF, Ferner R, Blesovsky A, Murray A, Pearson DT, James OF. Collins JD, et al. Among authors: james of. Lancet. 1983 May 21;1(8334):1119-23. doi: 10.1016/s0140-6736(83)92863-5. Lancet. 1983. PMID: 6133152
Development of PPJ was strongly associated with a bad outcome; 25% of jaundiced patients and 1% of non-jaundiced patients died in the postoperative period. The jaundice was a conjugated hyperbilirubinaemia, and was detectable in 48 out of 49 patients b …
Development of PPJ was strongly associated with a bad outcome; 25% of jaundiced patients and 1% of non-jaundiced patien …
Light microscopic and ultrastructural distribution of type VI collagen in human liver: alterations in chronic biliary disease.
Griffiths MR, Shepherd M, Ferrier R, Schuppan D, James OF, Burt AD. Griffiths MR, et al. Among authors: james of. Histopathology. 1992 Oct;21(4):335-44. doi: 10.1111/j.1365-2559.1992.tb00404.x. Histopathology. 1992. PMID: 1398536
Type III collagen was also found in the space of Disse although no significant intra-acinar variation in staining intensity was noted. ...The distribution of type VI collagen was also studied in biopsy material from patients with different histological stages of
Type III collagen was also found in the space of Disse although no significant intra-acinar variation in staining intensity was noted …
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