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Myc and Loss of p53 Cooperate to Drive Formation of Choroid Plexus Carcinoma.
Wang J, Merino DM, Light N, Murphy BL, Wang YD, Guo X, Hodges AP, Chau LQ, Liu KW, Dhall G, Asgharzadeh S, Kiehna EN, Shirey RJ, Janda KD, Taylor MD, Malkin D, Ellison DW, VandenBerg SR, Eberhart CG, Sears RC, Roussel MF, Gilbertson RJ, Wechsler-Reya RJ. Wang J, et al. Among authors: janda kd. Cancer Res. 2019 May 1;79(9):2208-2219. doi: 10.1158/0008-5472.CAN-18-2565. Epub 2019 Mar 18. Cancer Res. 2019. PMID: 30885981 Free PMC article.
Validation of onchocerciasis biomarker N-acetyltyramine-O-glucuronide (NATOG).
Globisch D, Eubanks LM, Shirey RJ, Pfarr KM, Wanji S, Debrah AY, Hoerauf A, Janda KD. Globisch D, et al. Among authors: janda kd. Bioorg Med Chem Lett. 2017 Aug 1;27(15):3436-3440. doi: 10.1016/j.bmcl.2017.05.082. Epub 2017 May 29. Bioorg Med Chem Lett. 2017. PMID: 28600214 Free PMC article.
Synthetic molecules for disruption of the MYC protein-protein interface.
Jacob NT, Miranda PO, Shirey RJ, Gautam R, Zhou B, de Orbe Izquierdo ME, Hixon MS, Hart JR, Ueno L, Vogt PK, Janda KD. Jacob NT, et al. Among authors: janda kd. Bioorg Med Chem. 2018 Aug 7;26(14):4234-4239. doi: 10.1016/j.bmc.2018.07.019. Epub 2018 Jul 11. Bioorg Med Chem. 2018. PMID: 30037753 Free PMC article.
Synthetic fluorescent MYC probe: Inhibitor binding site elucidation and development of a high-throughput screening assay.
Shirey RJ, Hart JR, Sridharan B, Novick SJ, Turner LD, Zhou B, Nielsen AL, Eubanks LM, Ueno L, Hixon MS, Lairson LL, Spicer TP, Scampavia LD, Griffin PR, Vogt PK, Janda KD. Shirey RJ, et al. Among authors: janda kd. Bioorg Med Chem. 2021 Jul 15;42:116246. doi: 10.1016/j.bmc.2021.116246. Epub 2021 Jun 6. Bioorg Med Chem. 2021. PMID: 34130216 Free PMC article.
456 results