Janet Brownlees[Author] - Search Results

Year	Number of Results
2002	1
2003	1
2004	2
2005	1
2007	1
2015	3
2018	1
2020	1
2021	1
2023	2
2024	1
2025	2

1

3D models of neurodegeneration: implementation in drug discovery.

Whitehouse C, Corbett N, Brownlees J. Whitehouse C, et al. Among authors: brownlees j. Trends Pharmacol Sci. 2023 Apr;44(4):208-221. doi: 10.1016/j.tips.2023.01.005. Epub 2023 Feb 22. Trends Pharmacol Sci. 2023. PMID: 36822950 Free article. Review.

2

Deficiency in NPC2 results in disruption of mitochondria-late endosome/lysosomes contact sites and endo-lysosomal lipid dyshomeostasis.

Pastore R, Yao L, Hatcher N, Helley M, Brownlees J, Desai R. Pastore R, et al. Among authors: brownlees j. Sci Rep. 2025 Jan 2;15(1):325. doi: 10.1038/s41598-024-83460-x. Sci Rep. 2025. PMID: 39747180 Free PMC article.

3

Three-Dimensional Bioprinting of Human iPSC-Derived Neuron-Astrocyte Cocultures for Screening Applications.

Whitehouse CA, He Y, Brownlees J, Corbett N. Whitehouse CA, et al. Among authors: brownlees j. J Vis Exp. 2023 Sep 29;(199). doi: 10.3791/65856. J Vis Exp. 2023. PMID: 37843292

4

Disrupting the interaction between AMBRA1 and DLC1 prevents apoptosis while enhancing autophagy and mitophagy.

Hawkins K, Watt M, Gillotin S, Hanspal M, Helley M, Richardson J, Corbett N, Brownlees J. Hawkins K, et al. Among authors: brownlees j. Biol Open. 2024 Dec 15;13(12):bio060380. doi: 10.1242/bio.060380. Epub 2024 Nov 26. Biol Open. 2024. PMID: 39469809 Free PMC article.

5

Development of a characterised tool kit for the interrogation of NLRP3 inflammasome-dependent responses.

Redondo-Castro E, Faust D, Fox S, Baldwin AG, Osborne S, Haley MJ, Karran E, Nuthall H, Atkinson PJ, Dawson LA, Routledge C, Allan SM, Freeman S, Brownlees J, Brough D. Redondo-Castro E, et al. Among authors: brownlees j. Sci Rep. 2018 Apr 4;8(1):5667. doi: 10.1038/s41598-018-24029-3. Sci Rep. 2018. PMID: 29618797 Free PMC article.

6

ALS2/Alsin regulates Rac-PAK signaling and neurite outgrowth.

Tudor EL, Perkinton MS, Schmidt A, Ackerley S, Brownlees J, Jacobsen NJ, Byers HL, Ward M, Hall A, Leigh PN, Shaw CE, McLoughlin DM, Miller CC. Tudor EL, et al. Among authors: brownlees j. J Biol Chem. 2005 Oct 14;280(41):34735-40. doi: 10.1074/jbc.M506216200. Epub 2005 Jul 26. J Biol Chem. 2005. PMID: 16049005 Free article.

7

Alzheimer therapy with an antibody against N-terminal Abeta 4-X and pyroglutamate Abeta 3-X.

Antonios G, Borgers H, Richard BC, Brauß A, Meißner J, Weggen S, Pena V, Pillot T, Davies SL, Bakrania P, Matthews D, Brownlees J, Bouter Y, Bayer TA. Antonios G, et al. Among authors: brownlees j. Sci Rep. 2015 Dec 2;5:17338. doi: 10.1038/srep17338. Sci Rep. 2015. PMID: 26626428 Free PMC article.

8

Catechols and 3-hydroxypyridones as inhibitors of the DNA repair complex ERCC1-XPF.

Chapman TM, Gillen KJ, Wallace C, Lee MT, Bakrania P, Khurana P, Coombs PJ, Stennett L, Fox S, Bureau EA, Brownlees J, Melton DW, Saxty B. Chapman TM, et al. Among authors: brownlees j. Bioorg Med Chem Lett. 2015 Oct 1;25(19):4097-103. doi: 10.1016/j.bmcl.2015.08.031. Epub 2015 Aug 17. Bioorg Med Chem Lett. 2015. PMID: 26318993

9

N-Hydroxyimides and hydroxypyrimidinones as inhibitors of the DNA repair complex ERCC1-XPF.

Chapman TM, Wallace C, Gillen KJ, Bakrania P, Khurana P, Coombs PJ, Fox S, Bureau EA, Brownlees J, Melton DW, Saxty B. Chapman TM, et al. Among authors: brownlees j. Bioorg Med Chem Lett. 2015 Oct 1;25(19):4104-8. doi: 10.1016/j.bmcl.2015.08.024. Epub 2015 Aug 14. Bioorg Med Chem Lett. 2015. PMID: 26321360

10

Charcot-Marie-Tooth disease neurofilament mutations disrupt neurofilament assembly and axonal transport.

Brownlees J, Ackerley S, Grierson AJ, Jacobsen NJ, Shea K, Anderton BH, Leigh PN, Shaw CE, Miller CC. Brownlees J, et al. Hum Mol Genet. 2002 Nov 1;11(23):2837-44. doi: 10.1093/hmg/11.23.2837. Hum Mol Genet. 2002. PMID: 12393795

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