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Cellular Immune Response Induced by DNA Immunization of Mice with Drug Resistant Integrases of HIV-1 Clade A Offers Partial Protection against Growth and Metastatic Activity of Integrase-Expressing Adenocarcinoma Cells.
Isaguliants M, Krotova O, Petkov S, Jansons J, Bayurova E, Mezale D, Fridrihsone I, Kilpelainen A, Podschwadt P, Agapkina Y, Smirnova O, Kostic L, Saleem M, Latyshev O, Eliseeva O, Malkova A, Gorodnicheva T, Wahren B, Gordeychuk I, Starodubova E, Latanova A. Isaguliants M, et al. Among authors: jansons j. Microorganisms. 2021 Jun 4;9(6):1219. doi: 10.3390/microorganisms9061219. Microorganisms. 2021. PMID: 34199989 Free PMC article.
Codon optimization and improved delivery/immunization regimen enhance the immune response against wild-type and drug-resistant HIV-1 reverse transcriptase, preserving its Th2-polarity.
Latanova AA, Petkov S, Kilpelainen A, Jansons J, Latyshev OE, Kuzmenko YV, Hinkula J, Abakumov MA, Valuev-Elliston VT, Gomelsky M, Karpov VL, Chiodi F, Wahren B, Logunov DY, Starodubova ES, Isaguliants MG. Latanova AA, et al. Among authors: jansons j. Sci Rep. 2018 May 24;8(1):8078. doi: 10.1038/s41598-018-26281-z. Sci Rep. 2018. PMID: 29799015 Free PMC article.
HIV-1 Reverse Transcriptase Promotes Tumor Growth and Metastasis Formation via ROS-Dependent Upregulation of Twist.
Bayurova E, Jansons J, Skrastina D, Smirnova O, Mezale D, Kostyusheva A, Kostyushev D, Petkov S, Podschwadt P, Valuev-Elliston V, Sasinovich S, Korolev S, Warholm P, Latanova A, Starodubova E, Tukhvatulin A, Latyshev O, Selimov R, Metalnikov P, Komarov A, Ivanova O, Gorodnicheva T, Kochetkov S, Gottikh M, Strumfa I, Ivanov A, Gordeychuk I, Isaguliants M. Bayurova E, et al. Among authors: jansons j. Oxid Med Cell Longev. 2019 Dec 2;2019:6016278. doi: 10.1155/2019/6016278. eCollection 2019. Oxid Med Cell Longev. 2019. PMID: 31885806 Free PMC article.
Expression of the Reverse Transcriptase Domain of Telomerase Reverse Transcriptase Induces Lytic Cellular Response in DNA-Immunized Mice and Limits Tumorigenic and Metastatic Potential of Murine Adenocarcinoma 4T1 Cells.
Jansons J, Bayurova E, Skrastina D, Kurlanda A, Fridrihsone I, Kostyushev D, Kostyusheva A, Artyuhov A, Dashinimaev E, Avdoshina D, Kondrashova A, Valuev-Elliston V, Latyshev O, Eliseeva O, Petkov S, Abakumov M, Hippe L, Kholodnyuk I, Starodubova E, Gorodnicheva T, Ivanov A, Gordeychuk I, Isaguliants M. Jansons J, et al. Vaccines (Basel). 2020 Jun 18;8(2):318. doi: 10.3390/vaccines8020318. Vaccines (Basel). 2020. PMID: 32570805 Free PMC article.
48 results