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Respond to "No antigen-presentation defect in Unc93b1(3d/3d) (3d) mice".
Tabeta K, Hoebe K, Janssen EM, Xia Y, Beutler B. Tabeta K, et al. Among authors: janssen em. Nat Immunol. 2013 Nov;14(11):1102-3. doi: 10.1038/ni.2734. Nat Immunol. 2013. PMID: 24145779 No abstract available.
Identification of Lps2 as a key transducer of MyD88-independent TIR signalling.
Hoebe K, Du X, Georgel P, Janssen E, Tabeta K, Kim SO, Goode J, Lin P, Mann N, Mudd S, Crozat K, Sovath S, Han J, Beutler B. Hoebe K, et al. Nature. 2003 Aug 14;424(6950):743-8. doi: 10.1038/nature01889. Epub 2003 Jul 20. Nature. 2003. PMID: 12872135
The Unc93b1 mutation 3d disrupts exogenous antigen presentation and signaling via Toll-like receptors 3, 7 and 9.
Tabeta K, Hoebe K, Janssen EM, Du X, Georgel P, Crozat K, Mudd S, Mann N, Sovath S, Goode J, Shamel L, Herskovits AA, Portnoy DA, Cooke M, Tarantino LM, Wiltshire T, Steinberg BE, Grinstein S, Beutler B. Tabeta K, et al. Among authors: janssen em. Nat Immunol. 2006 Feb;7(2):156-64. doi: 10.1038/ni1297. Epub 2006 Jan 15. Nat Immunol. 2006. PMID: 16415873
CD4+ T-cell help controls CD8+ T-cell memory via TRAIL-mediated activation-induced cell death.
Janssen EM, Droin NM, Lemmens EE, Pinkoski MJ, Bensinger SJ, Ehst BD, Griffith TS, Green DR, Schoenberger SP. Janssen EM, et al. Nature. 2005 Mar 3;434(7029):88-93. doi: 10.1038/nature03337. Nature. 2005. PMID: 15744305
Upregulation of costimulatory molecules induced by lipopolysaccharide and double-stranded RNA occurs by Trif-dependent and Trif-independent pathways.
Hoebe K, Janssen EM, Kim SO, Alexopoulou L, Flavell RA, Han J, Beutler B. Hoebe K, et al. Among authors: janssen em. Nat Immunol. 2003 Dec;4(12):1223-9. doi: 10.1038/ni1010. Epub 2003 Nov 16. Nat Immunol. 2003. PMID: 14625548
The interface between innate and adaptive immunity.
Hoebe K, Janssen E, Beutler B. Hoebe K, et al. Nat Immunol. 2004 Oct;5(10):971-4. doi: 10.1038/ni1004-971. Nat Immunol. 2004. PMID: 15454919 Review.
Kinase MEKK1 is required for CD40-dependent activation of the kinases Jnk and p38, germinal center formation, B cell proliferation and antibody production.
Gallagher E, Enzler T, Matsuzawa A, Anzelon-Mills A, Otero D, Holzer R, Janssen E, Gao M, Karin M. Gallagher E, et al. Nat Immunol. 2007 Jan;8(1):57-63. doi: 10.1038/ni1421. Epub 2006 Dec 3. Nat Immunol. 2007. PMID: 17143273
IFN-gamma and self-absorbed CD4+ T cells: a regulatory double negative.
Hildeman D, Janssen E. Hildeman D, et al. Nat Immunol. 2008 Nov;9(11):1210-2. doi: 10.1038/ni1108-1210. Nat Immunol. 2008. PMID: 18936780 Free PMC article.
STING, DCs and the link between innate and adaptive tumor immunity.
Vatner RE, Janssen EM. Vatner RE, et al. Among authors: janssen em. Mol Immunol. 2019 Jun;110:13-23. doi: 10.1016/j.molimm.2017.12.001. Epub 2017 Dec 20. Mol Immunol. 2019. PMID: 29273394 Free PMC article. Review.
STING-mediated DNA sensing promotes antitumor and autoimmune responses to dying cells.
Klarquist J, Hennies CM, Lehn MA, Reboulet RA, Feau S, Janssen EM. Klarquist J, et al. Among authors: janssen em. J Immunol. 2014 Dec 15;193(12):6124-34. doi: 10.4049/jimmunol.1401869. Epub 2014 Nov 10. J Immunol. 2014. PMID: 25385820 Free PMC article.
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