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An enzymatically inactivated hemoglobinase from Necator americanus induces neutralizing antibodies against multiple hookworm species and protects dogs against heterologous hookworm infection.
Pearson MS, Bethony JM, Pickering DA, de Oliveira LM, Jariwala A, Santiago H, Miles AP, Zhan B, Jiang D, Ranjit N, Mulvenna J, Tribolet L, Plieskatt J, Smith T, Bottazzi ME, Jones K, Keegan B, Hotez PJ, Loukas A. Pearson MS, et al. Among authors: jariwala a. FASEB J. 2009 Sep;23(9):3007-19. doi: 10.1096/fj.09-131433. Epub 2009 Apr 20. FASEB J. 2009. PMID: 19380510 Free PMC article.
Potency testing for the experimental Na-GST-1 hookworm vaccine.
Jariwala AR, Oliveira LM, Diemert DJ, Keegan B, Plieskatt JL, Periago MV, Bottazzi ME, Hotez PJ, Bethony JM. Jariwala AR, et al. Expert Rev Vaccines. 2010 Oct;9(10):1219-30. doi: 10.1586/erv.10.107. Expert Rev Vaccines. 2010. PMID: 20923271 Review.
A history of hookworm vaccine development.
Schneider B, Jariwala AR, Periago MV, Gazzinelli MF, Bose SN, Hotez PJ, Diemert DJ, Bethony JM. Schneider B, et al. Hum Vaccin. 2011 Nov;7(11):1234-44. doi: 10.4161/hv.7.11.18443. Epub 2011 Nov 1. Hum Vaccin. 2011. PMID: 22064562 Free PMC article. Review.
Molecular mechanisms of hookworm disease: stealth, virulence, and vaccines.
Pearson MS, Tribolet L, Cantacessi C, Periago MV, Valero MA, Jariwala AR, Hotez P, Diemert D, Loukas A, Bethony J. Pearson MS, et al. Among authors: jariwala ar. J Allergy Clin Immunol. 2012 Jul;130(1):13-21. doi: 10.1016/j.jaci.2012.05.029. J Allergy Clin Immunol. 2012. PMID: 22742835 Review.
Generalized urticaria induced by the Na-ASP-2 hookworm vaccine: implications for the development of vaccines against helminths.
Diemert DJ, Pinto AG, Freire J, Jariwala A, Santiago H, Hamilton RG, Periago MV, Loukas A, Tribolet L, Mulvenna J, Correa-Oliveira R, Hotez PJ, Bethony JM. Diemert DJ, et al. Among authors: jariwala a. J Allergy Clin Immunol. 2012 Jul;130(1):169-76.e6. doi: 10.1016/j.jaci.2012.04.027. Epub 2012 May 26. J Allergy Clin Immunol. 2012. PMID: 22633322 Clinical Trial.
Advances in neglected tropical disease vaccines: Developing relative potency and functional assays for the Na-GST-1/Alhydrogel hookworm vaccine.
Brelsford JB, Plieskatt JL, Yakovleva A, Jariwala A, Keegan BP, Peng J, Xia P, Li G, Campbell D, Periago MV, Correa-Oliveira R, Bottazzi ME, Hotez PJ, Diemert D, Bethony JM. Brelsford JB, et al. Among authors: jariwala a. PLoS Negl Trop Dis. 2017 Feb 13;11(2):e0005385. doi: 10.1371/journal.pntd.0005385. eCollection 2017 Feb. PLoS Negl Trop Dis. 2017. PMID: 28192438 Free PMC article.
Safety and immunogenicity of the Na-GST-1 hookworm vaccine in Brazilian and American adults.
Diemert DJ, Freire J, Valente V, Fraga CG, Talles F, Grahek S, Campbell D, Jariwala A, Periago MV, Enk M, Gazzinelli MF, Bottazzi ME, Hamilton R, Brelsford J, Yakovleva A, Li G, Peng J, Correa-Oliveira R, Hotez P, Bethony J. Diemert DJ, et al. Among authors: jariwala a. PLoS Negl Trop Dis. 2017 May 2;11(5):e0005574. doi: 10.1371/journal.pntd.0005574. eCollection 2017 May. PLoS Negl Trop Dis. 2017. PMID: 28464026 Free PMC article. Clinical Trial.
Expression, immunogenicity, histopathology, and potency of a mosquito-based malaria transmission-blocking recombinant vaccine.
Mathias DK, Plieskatt JL, Armistead JS, Bethony JM, Abdul-Majid KB, McMillan A, Angov E, Aryee MJ, Zhan B, Gillespie P, Keegan B, Jariwala AR, Rezende W, Bottazzi ME, Scorpio DG, Hotez PJ, Dinglasan RR. Mathias DK, et al. Among authors: jariwala ar. Infect Immun. 2012 Apr;80(4):1606-14. doi: 10.1128/IAI.06212-11. Epub 2012 Feb 6. Infect Immun. 2012. PMID: 22311924 Free PMC article.
Levels of 8-OxodG Predict Hepatobiliary Pathology in Opisthorchis viverrini Endemic Settings in Thailand.
Saichua P, Yakovleva A, Kamamia C, Jariwala AR, Sithithaworn J, Sripa B, Brindley PJ, Laha T, Mairiang E, Pairojkul C, Khuntikeo N, Mulvenna J, Sithithaworn P, Bethony JM. Saichua P, et al. Among authors: jariwala ar. PLoS Negl Trop Dis. 2015 Jul 31;9(7):e0003949. doi: 10.1371/journal.pntd.0003949. eCollection 2015. PLoS Negl Trop Dis. 2015. PMID: 26230769 Free PMC article.
59 results