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TGF-β regulates DNA methyltransferase expression in prostate cancer, correlates with aggressive capabilities, and predicts disease recurrence.
Zhang Q, Chen L, Helfand BT, Jang TL, Sharma V, Kozlowski J, Kuzel TM, Zhu LJ, Yang XJ, Javonovic B, Guo Y, Lonning S, Harper J, Teicher BA, Brendler C, Yu N, Catalona WJ, Lee C. Zhang Q, et al. Among authors: javonovic b. PLoS One. 2011;6(9):e25168. doi: 10.1371/journal.pone.0025168. Epub 2011 Sep 30. PLoS One. 2011. PMID: 21980391 Free PMC article.
Nuclear factor-kappaB-mediated transforming growth factor-beta-induced expression of vimentin is an independent predictor of biochemical recurrence after radical prostatectomy.
Zhang Q, Helfand BT, Jang TL, Zhu LJ, Chen L, Yang XJ, Kozlowski J, Smith N, Kundu SD, Yang G, Raji AA, Javonovic B, Pins M, Lindholm P, Guo Y, Catalona WJ, Lee C. Zhang Q, et al. Among authors: javonovic b. Clin Cancer Res. 2009 May 15;15(10):3557-67. doi: 10.1158/1078-0432.CCR-08-1656. Epub 2009 May 15. Clin Cancer Res. 2009. PMID: 19447876
Infiltration of tumor-reactive transforming growth factor-beta insensitive CD8+ T cells into the tumor parenchyma is associated with apoptosis and rejection of tumor cells.
Zhang Q, Jang TL, Yang X, Park I, Meyer RE, Kundu S, Pins M, Javonovic B, Kuzel T, Kim SJ, Van Parijs L, Smith N, Wong L, Greenberg NM, Guo Y, Lee C. Zhang Q, et al. Among authors: javonovic b. Prostate. 2006 Feb 15;66(3):235-47. doi: 10.1002/pros.20340. Prostate. 2006. PMID: 16173028