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Photoactivated azido fatty acid irreversibly inhibits anion and proton transport through the mitochondrial uncoupling protein.
Jezek P, Hanus J, Semrad C, Garlid KD. Jezek P, et al. J Biol Chem. 1996 Mar 15;271(11):6199-205. doi: 10.1074/jbc.271.11.6199. J Biol Chem. 1996. PMID: 8626410 Free article.
The protonophoretic function of uncoupling protein (UCP) is activated by fatty acids. According to the "docking site" hypothesis (Jezek, P., and Garlid, K. D., J. Biol. Chem. 265, 19303-19311, 1990), the fatty acid binding site is identical with the anion channel of …
The protonophoretic function of uncoupling protein (UCP) is activated by fatty acids. According to the "docking site" hypothesis (Jezek …
263 results