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Dipeptide-based highly potent doxorubicin antibody conjugates.
Jeffrey SC, Nguyen MT, Andreyka JB, Meyer DL, Doronina SO, Senter PD. Jeffrey SC, et al. Bioorg Med Chem Lett. 2006 Jan 15;16(2):358-62. doi: 10.1016/j.bmcl.2005.09.081. Epub 2005 Nov 3. Bioorg Med Chem Lett. 2006. PMID: 16275070
A potent anti-CD70 antibody-drug conjugate combining a dimeric pyrrolobenzodiazepine drug with site-specific conjugation technology.
Jeffrey SC, Burke PJ, Lyon RP, Meyer DW, Sussman D, Anderson M, Hunter JH, Leiske CI, Miyamoto JB, Nicholas ND, Okeley NM, Sanderson RJ, Stone IJ, Zeng W, Gregson SJ, Masterson L, Tiberghien AC, Howard PW, Thurston DE, Law CL, Senter PD. Jeffrey SC, et al. Bioconjug Chem. 2013 Jul 17;24(7):1256-63. doi: 10.1021/bc400217g. Epub 2013 Jun 28. Bioconjug Chem. 2013. PMID: 23808985
Development of Novel Quaternary Ammonium Linkers for Antibody-Drug Conjugates.
Burke PJ, Hamilton JZ, Pires TA, Setter JR, Hunter JH, Cochran JH, Waight AB, Gordon KA, Toki BE, Emmerton KK, Zeng W, Stone IJ, Senter PD, Lyon RP, Jeffrey SC. Burke PJ, et al. Among authors: jeffrey sc. Mol Cancer Ther. 2016 May;15(5):938-45. doi: 10.1158/1535-7163.MCT-16-0038. Epub 2016 Mar 4. Mol Cancer Ther. 2016. PMID: 26944920
32 results