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Epigenetic Restoration of Fetal-like IGF1 Signaling Inhibits Leukemia Stem Cell Activity.
Giambra V, Gusscott S, Gracias D, Song R, Lam SH, Panelli P, Tyshchenko K, Jenkins CE, Hoofd C, Lorzadeh A, Carles A, Hirst M, Eaves CJ, Weng AP. Giambra V, et al. Among authors: jenkins ce. Cell Stem Cell. 2018 Nov 1;23(5):714-726.e7. doi: 10.1016/j.stem.2018.08.018. Epub 2018 Sep 27. Cell Stem Cell. 2018. PMID: 30269902 Free article.
Leukemia stem cells in T-ALL require active Hif1α and Wnt signaling.
Giambra V, Jenkins CE, Lam SH, Hoofd C, Belmonte M, Wang X, Gusscott S, Gracias D, Weng AP. Giambra V, et al. Among authors: jenkins ce. Blood. 2015 Jun 18;125(25):3917-27. doi: 10.1182/blood-2014-10-609370. Epub 2015 May 1. Blood. 2015. PMID: 25934477 Free PMC article.
Targeting transcription regulation in cancer with a covalent CDK7 inhibitor.
Kwiatkowski N, Zhang T, Rahl PB, Abraham BJ, Reddy J, Ficarro SB, Dastur A, Amzallag A, Ramaswamy S, Tesar B, Jenkins CE, Hannett NM, McMillin D, Sanda T, Sim T, Kim ND, Look T, Mitsiades CS, Weng AP, Brown JR, Benes CH, Marto JA, Young RA, Gray NS. Kwiatkowski N, et al. Among authors: jenkins ce. Nature. 2014 Jul 31;511(7511):616-20. doi: 10.1038/nature13393. Epub 2014 Jun 22. Nature. 2014. PMID: 25043025 Free PMC article.
45 results