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Risk factors and prevention of cardiotoxicity induced by 5-fluorouracil or capecitabine.
Jensen SA, Sørensen JB. Jensen SA, et al. Cancer Chemother Pharmacol. 2006 Oct;58(4):487-93. doi: 10.1007/s00280-005-0178-1. Epub 2006 Jan 18. Cancer Chemother Pharmacol. 2006. PMID: 16418875
Combinations of polymorphisms in genes involved in the 5-Fluorouracil metabolism pathway are associated with gastrointestinal toxicity in chemotherapy-treated colorectal cancer patients.
Afzal S, Gusella M, Vainer B, Vogel UB, Andersen JT, Broedbaek K, Petersen M, Jimenez-Solem E, Bertolaso L, Barile C, Padrini R, Pasini F, Jensen SA, Poulsen HE. Afzal S, et al. Clin Cancer Res. 2011 Jun 1;17(11):3822-9. doi: 10.1158/1078-0432.CCR-11-0304. Epub 2011 Apr 6. Clin Cancer Res. 2011. PMID: 21471424
5-fluorouracil-based therapy induces endovascular injury having potential significance to development of clinically overt cardiotoxicity.
Jensen SA, Sørensen JB. Jensen SA, et al. Cancer Chemother Pharmacol. 2012 Jan;69(1):57-64. doi: 10.1007/s00280-011-1669-x. Epub 2011 May 21. Cancer Chemother Pharmacol. 2012. PMID: 21603868
The association of polymorphisms in 5-fluorouracil metabolism genes with outcome in adjuvant treatment of colorectal cancer.
Afzal S, Gusella M, Jensen SA, Vainer B, Vogel U, Andersen JT, Brødbæk K, Petersen M, Jimenez-Solem E, Adleff V, Budai B, Hitre E, Láng I, Orosz E, Bertolaso L, Barile C, Padrini R, Kralovánszky J, Pasini F, Poulsen HE. Afzal S, et al. Pharmacogenomics. 2011 Sep;12(9):1257-67. doi: 10.2217/pgs.11.83. Pharmacogenomics. 2011. PMID: 21919605
Oxidative damage to guanine nucleosides following combination chemotherapy with 5-fluorouracil and oxaliplatin.
Afzal S, Jensen SA, Sørensen JB, Henriksen T, Weimann A, Poulsen HE. Afzal S, et al. Cancer Chemother Pharmacol. 2012 Feb;69(2):301-7. doi: 10.1007/s00280-011-1700-2. Epub 2011 Jun 28. Cancer Chemother Pharmacol. 2012. PMID: 21710244 Clinical Trial.
Fluorouracil induces myocardial ischemia with increases of plasma brain natriuretic peptide and lactic acid but without dysfunction of left ventricle.
Jensen SA, Hasbak P, Mortensen J, Sørensen JB. Jensen SA, et al. J Clin Oncol. 2010 Dec 20;28(36):5280-6. doi: 10.1200/JCO.2009.27.3953. Epub 2010 Nov 15. J Clin Oncol. 2010. PMID: 21079148 Clinical Trial.
[Cardiotoxicity induced by 5-fluorouracil or capecitabine].
Jensen SA, Baeksgaard L, Petersen LN, Reiter L, Sørensen JB. Jensen SA, et al. Ugeskr Laeger. 2010 Jan 4;172(1):48-51. Ugeskr Laeger. 2010. PMID: 20056096 Danish.
Prognostic significance of numeric aberrations of genes for thymidylate synthase, thymidine phosphorylase and dihydrofolate reductase in colorectal cancer.
Jensen SA, Vainer B, Witton CJ, Jørgensen JT, Sørensen JB. Jensen SA, et al. Acta Oncol. 2008;47(6):1054-61. doi: 10.1080/02841860801942158. Acta Oncol. 2008. PMID: 18607850
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