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To degrade or not to degrade: how phase separation modulates selective autophagy.
Autophagy. 2025 Mar 12:1-3. doi: 10.1080/15548627.2025.2476025. Online ahead of print.
Autophagy. 2025.
PMID: 40052694
Free article.
Osmotic stress induces formation of both liquid condensates and amyloids by a yeast prion domain.
Grizel AV, Gorsheneva NA, Stevenson JB, Pflaum J, Wilfling F, Rubel AA, Chernoff YO.
Grizel AV, et al. Among authors: pflaum j.
J Biol Chem. 2024 Oct;300(10):107766. doi: 10.1016/j.jbc.2024.107766. Epub 2024 Sep 12.
J Biol Chem. 2024.
PMID: 39276934
Free PMC article.
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Phase separation of initiation hubs on cargo is a trigger switch for selective autophagy.
Licheva M, Pflaum J, Babic R, Mancilla H, Elsässer J, Boyle E, Hollenstein DM, Jimenez-Niebla J, Pleyer J, Heinrich M, Wieland FG, Brenneisen J, Eickhorst C, Brenner J, Jiang S, Hartl M, Welsch S, Hunte C, Timmer J, Wilfling F, Kraft C.
Licheva M, et al. Among authors: pflaum j.
Nat Cell Biol. 2025 Feb;27(2):283-297. doi: 10.1038/s41556-024-01572-y. Epub 2025 Jan 7.
Nat Cell Biol. 2025.
PMID: 39774270
Free PMC article.
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Regulation of somatic hypermutation by higher-order chromatin structure.
Schoeberl UE, Fitz J, von der Linde M, Valieris R, Bauer B, Malzl D, Froussios K, Costea J, Schmidt F, Pflaum J, Bartl B, Albrecht J, Wiedemann EM, Garcia AC, Peycheva M, Rizzi M, Goloborodko A, Tojal da Silva I, Pavri R.
Schoeberl UE, et al. Among authors: pflaum j.
Mol Cell. 2025 Jun 20:S1097-2765(25)00503-9. doi: 10.1016/j.molcel.2025.06.003. Online ahead of print.
Mol Cell. 2025.
PMID: 40580953
Free article.
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