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NFIA co-localizes with PPARγ and transcriptionally controls the brown fat gene program.
Hiraike Y, Waki H, Yu J, Nakamura M, Miyake K, Nagano G, Nakaki R, Suzuki K, Kobayashi H, Yamamoto S, Sun W, Aoyama T, Hirota Y, Ohno H, Oki K, Yoneda M, White AP, Tseng YH, Cypess AM, Larsen TJ, Jespersen NZ, Scheele C, Tsutsumi S, Aburatani H, Yamauchi T, Kadowaki T. Hiraike Y, et al. Among authors: jespersen nz. Nat Cell Biol. 2017 Sep;19(9):1081-1092. doi: 10.1038/ncb3590. Epub 2017 Aug 14. Nat Cell Biol. 2017. PMID: 28812581 Free PMC article.
FGF21 Is a Sugar-Induced Hormone Associated with Sweet Intake and Preference in Humans.
Søberg S, Sandholt CH, Jespersen NZ, Toft U, Madsen AL, von Holstein-Rathlou S, Grevengoed TJ, Christensen KB, Bredie WLP, Potthoff MJ, Solomon TPJ, Scheele C, Linneberg A, Jørgensen T, Pedersen O, Hansen T, Gillum MP, Grarup N. Søberg S, et al. Among authors: jespersen nz. Cell Metab. 2017 May 2;25(5):1045-1053.e6. doi: 10.1016/j.cmet.2017.04.009. Cell Metab. 2017. PMID: 28467924 Free article.
Brown Fat AKT2 Is a Cold-Induced Kinase that Stimulates ChREBP-Mediated De Novo Lipogenesis to Optimize Fuel Storage and Thermogenesis.
Sanchez-Gurmaches J, Tang Y, Jespersen NZ, Wallace M, Martinez Calejman C, Gujja S, Li H, Edwards YJK, Wolfrum C, Metallo CM, Nielsen S, Scheele C, Guertin DA. Sanchez-Gurmaches J, et al. Among authors: jespersen nz. Cell Metab. 2018 Jan 9;27(1):195-209.e6. doi: 10.1016/j.cmet.2017.10.008. Epub 2017 Nov 16. Cell Metab. 2018. PMID: 29153407 Free PMC article.
Cardiolipin Synthesis in Brown and Beige Fat Mitochondria Is Essential for Systemic Energy Homeostasis.
Sustarsic EG, Ma T, Lynes MD, Larsen M, Karavaeva I, Havelund JF, Nielsen CH, Jedrychowski MP, Moreno-Torres M, Lundh M, Plucinska K, Jespersen NZ, Grevengoed TJ, Kramar B, Peics J, Hansen JB, Shamsi F, Forss I, Neess D, Keipert S, Wang J, Stohlmann K, Brandslund I, Christensen C, Jørgensen ME, Linneberg A, Pedersen O, Kiebish MA, Qvortrup K, Han X, Pedersen BK, Jastroch M, Mandrup S, Kjær A, Gygi SP, Hansen T, Gillum MP, Grarup N, Emanuelli B, Nielsen S, Scheele C, Tseng YH, Færgeman NJ, Gerhart-Hines Z. Sustarsic EG, et al. Among authors: jespersen nz. Cell Metab. 2018 Jul 3;28(1):159-174.e11. doi: 10.1016/j.cmet.2018.05.003. Epub 2018 May 31. Cell Metab. 2018. PMID: 29861389 Free PMC article.
Adipogenesis in Primary Cell Culture.
Larsen TJ, Jespersen NZ, Scheele C. Larsen TJ, et al. Among authors: jespersen nz. Handb Exp Pharmacol. 2019;251:73-84. doi: 10.1007/164_2018_142. Handb Exp Pharmacol. 2019. PMID: 29980911
Gamma-Aminobutyric Acid Signaling in Brown Adipose Tissue Promotes Systemic Metabolic Derangement in Obesity.
Ikegami R, Shimizu I, Sato T, Yoshida Y, Hayashi Y, Suda M, Katsuumi G, Li J, Wakasugi T, Minokoshi Y, Okamoto S, Hinoi E, Nielsen S, Jespersen NZ, Scheele C, Soga T, Minamino T. Ikegami R, et al. Among authors: jespersen nz. Cell Rep. 2018 Sep 11;24(11):2827-2837.e5. doi: 10.1016/j.celrep.2018.08.024. Cell Rep. 2018. PMID: 30208310 Free article.
Osteogenesis depends on commissioning of a network of stem cell transcription factors that act as repressors of adipogenesis.
Rauch A, Haakonsson AK, Madsen JGS, Larsen M, Forss I, Madsen MR, Van Hauwaert EL, Wiwie C, Jespersen NZ, Tencerova M, Nielsen R, Larsen BD, Röttger R, Baumbach J, Scheele C, Kassem M, Mandrup S. Rauch A, et al. Among authors: jespersen nz. Nat Genet. 2019 Apr;51(4):716-727. doi: 10.1038/s41588-019-0359-1. Epub 2019 Mar 4. Nat Genet. 2019. PMID: 30833796
Author Correction: Osteogenesis depends on commissioning of a network of stem cell transcription factors that act as repressors of adipogenesis.
Rauch A, Haakonsson AK, Madsen JGS, Larsen M, Forss I, Madsen MR, Van Hauwaert EL, Wiwie C, Jespersen NZ, Tencerova M, Nielsen R, Larsen BD, Röttger R, Baumbach J, Scheele C, Kassem M, Mandrup S. Rauch A, et al. Among authors: jespersen nz. Nat Genet. 2019 Apr;51(4):766. doi: 10.1038/s41588-019-0400-4. Nat Genet. 2019. PMID: 30911162
Heterogeneity in the perirenal region of humans suggests presence of dormant brown adipose tissue that contains brown fat precursor cells.
Jespersen NZ, Feizi A, Andersen ES, Heywood S, Hattel HB, Daugaard S, Peijs L, Bagi P, Feldt-Rasmussen B, Schultz HS, Hansen NS, Krogh-Madsen R, Pedersen BK, Petrovic N, Nielsen S, Scheele C. Jespersen NZ, et al. Mol Metab. 2019 Jun;24:30-43. doi: 10.1016/j.molmet.2019.03.005. Epub 2019 Mar 15. Mol Metab. 2019. PMID: 31079959 Free PMC article.
25 results