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Steroid-induced fibroblast growth factors drive an epithelial-mesenchymal inflammatory axis in severe asthma.
Guidi R, Xu D, Choy DF, Ramalingam TR, Lee WP, Modrusan Z, Liang Y, Marsters S, Ashkenazi A, Huynh A, Mills J, Flanagan S, Hambro S, Nunez V, Leong L, Cook A, Tran TH, Austin CD, Cao Y, Clarke C, Panettieri RA Jr, Koziol-White C, Jester WF Jr, Wang F, Wilson MS. Guidi R, et al. Among authors: jester wf jr. Sci Transl Med. 2022 Apr 20;14(641):eabl8146. doi: 10.1126/scitranslmed.abl8146. Epub 2022 Apr 20. Sci Transl Med. 2022. PMID: 35442706 Free PMC article.
Oncostatin M expression induced by bacterial triggers drives airway inflammatory and mucus secretion in severe asthma.
Headland SE, Dengler HS, Xu D, Teng G, Everett C, Ratsimandresy RA, Yan D, Kang J, Ganeshan K, Nazarova EV, Gierke S, Wedeles CJ, Guidi R, DePianto DJ, Morshead KB, Huynh A, Mills J, Flanagan S, Hambro S, Nunez V, Klementowicz JE, Shi Y, Wang J, Bevers J 3rd, Ramirez-Carrozzi V, Pappu R, Abbas A, Vander Heiden J, Choy DF, Yadav R, Modrusan Z, Panettieri RA Jr, Koziol-White C, Jester WF Jr, Jenkins BJ, Cao Y, Clarke C, Austin C, Lafkas D, Xu M, Wolters PJ, Arron JR, West NR, Wilson MS. Headland SE, et al. Among authors: jester wf jr. Sci Transl Med. 2022 Jan 12;14(627):eabf8188. doi: 10.1126/scitranslmed.abf8188. Epub 2022 Jan 12. Sci Transl Med. 2022. PMID: 35020406
An inherent dysfunction in soluble guanylyl cyclase is present in the airway of severe asthmatics and is associated with aberrant redox enzyme expression and compromised NO-cGMP signaling.
Ghosh A, Koziol-White CJ, Jester WF Jr, Erzurum SC, Asosingh K, Panettieri RA Jr, Stuehr DJ. Ghosh A, et al. Among authors: jester wf jr. Redox Biol. 2021 Feb;39:101832. doi: 10.1016/j.redox.2020.101832. Epub 2020 Dec 13. Redox Biol. 2021. PMID: 33360351 Free PMC article.
Elastomeric sensor surfaces for high-throughput single-cell force cytometry.
Pushkarsky I, Tseng P, Black D, France B, Warfe L, Koziol-White CJ, Jester WF Jr, Trinh RK, Lin J, Scumpia PO, Morrison SL, Panettieri RA Jr, Damoiseaux R, Di Carlo D. Pushkarsky I, et al. Among authors: jester wf jr. Nat Biomed Eng. 2018 Feb;2(2):124-137. doi: 10.1038/s41551-018-0193-2. Epub 2018 Feb 6. Nat Biomed Eng. 2018. PMID: 31015629 Free PMC article.
TGF-beta potentiates airway smooth muscle responsiveness to bradykinin.
Kim JH, Jain D, Tliba O, Yang B, Jester WF Jr, Panettieri RA Jr, Amrani Y, Puré E. Kim JH, et al. Among authors: jester wf jr. Am J Physiol Lung Cell Mol Physiol. 2005 Oct;289(4):L511-20. doi: 10.1152/ajplung.00027.2005. Epub 2005 May 27. Am J Physiol Lung Cell Mol Physiol. 2005. PMID: 15923209 Free article.
18 results