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Brain energy rescue: an emerging therapeutic concept for neurodegenerative disorders of ageing.
Cunnane SC, Trushina E, Morland C, Prigione A, Casadesus G, Andrews ZB, Beal MF, Bergersen LH, Brinton RD, de la Monte S, Eckert A, Harvey J, Jeggo R, Jhamandas JH, Kann O, la Cour CM, Martin WF, Mithieux G, Moreira PI, Murphy MP, Nave KA, Nuriel T, Oliet SHR, Saudou F, Mattson MP, Swerdlow RH, Millan MJ. Cunnane SC, et al. Among authors: jhamandas jh. Nat Rev Drug Discov. 2020 Sep;19(9):609-633. doi: 10.1038/s41573-020-0072-x. Epub 2020 Jul 24. Nat Rev Drug Discov. 2020. PMID: 32709961 Review.
Amylin Receptor: A Potential Therapeutic Target for Alzheimer's Disease.
Fu W, Patel A, Kimura R, Soudy R, Jhamandas JH. Fu W, et al. Among authors: jhamandas jh. Trends Mol Med. 2017 Aug;23(8):709-720. doi: 10.1016/j.molmed.2017.06.003. Epub 2017 Jul 7. Trends Mol Med. 2017. PMID: 28694141 Review.
Pramlintide Antagonizes Beta Amyloid (Aβ)- and Human Amylin-Induced Depression of Hippocampal Long-Term Potentiation.
Kimura R, MacTavish D, Yang J, Westaway D, Jhamandas JH. Kimura R, et al. Among authors: jhamandas jh. Mol Neurobiol. 2017 Jan;54(1):748-754. doi: 10.1007/s12035-016-9684-x. Epub 2016 Jan 15. Mol Neurobiol. 2017. PMID: 26768593
Bioenergetic mechanisms in astrocytes may contribute to amyloid plaque deposition and toxicity.
Fu W, Shi D, Westaway D, Jhamandas JH. Fu W, et al. Among authors: jhamandas jh. J Biol Chem. 2015 May 15;290(20):12504-13. doi: 10.1074/jbc.M114.618157. Epub 2015 Mar 26. J Biol Chem. 2015. PMID: 25814669 Free PMC article.
Histamine induces the production of matrix metalloproteinase-9 in human astrocytic cultures via H1-receptor subtype.
Patel A, Vasanthan V, Fu W, Fahlman RP, MacTavish D, Jhamandas JH. Patel A, et al. Among authors: jhamandas jh. Brain Struct Funct. 2016 May;221(4):1845-60. doi: 10.1007/s00429-015-1007-x. Epub 2015 Feb 15. Brain Struct Funct. 2016. PMID: 25682263
The hypothalamic neuropeptide FF network is impaired in hypertensive patients.
Goncharuk VD, Buijs RM, Jhamandas JH, Swaab DF. Goncharuk VD, et al. Among authors: jhamandas jh. Brain Behav. 2014 Jul;4(4):453-67. doi: 10.1002/brb3.229. Epub 2014 Apr 10. Brain Behav. 2014. PMID: 25161813 Free PMC article.
Role of astrocytic glycolytic metabolism in Alzheimer's disease pathogenesis.
Fu W, Jhamandas JH. Fu W, et al. Among authors: jhamandas jh. Biogerontology. 2014 Dec;15(6):579-86. doi: 10.1007/s10522-014-9525-0. Epub 2014 Aug 9. Biogerontology. 2014. PMID: 25106114 Review.
The prion protein modulates A-type K+ currents mediated by Kv4.2 complexes through dipeptidyl aminopeptidase-like protein 6.
Mercer RC, Ma L, Watts JC, Strome R, Wohlgemuth S, Yang J, Cashman NR, Coulthart MB, Schmitt-Ulms G, Jhamandas JH, Westaway D. Mercer RC, et al. Among authors: jhamandas jh. J Biol Chem. 2013 Dec 27;288(52):37241-55. doi: 10.1074/jbc.M113.488650. Epub 2013 Nov 13. J Biol Chem. 2013. PMID: 24225951 Free PMC article.
Amylin receptor: a common pathophysiological target in Alzheimer's disease and diabetes mellitus.
Fu W, Patel A, Jhamandas JH. Fu W, et al. Among authors: jhamandas jh. Front Aging Neurosci. 2013 Aug 15;5:42. doi: 10.3389/fnagi.2013.00042. eCollection 2013. Front Aging Neurosci. 2013. PMID: 23966942 Free PMC article.
Activity and metabolism-related Ca2+ and mitochondrial dynamics in co-cultured human fetal cortical neurons and astrocytes.
Fu W, Ruangkittisakul A, MacTavish D, Baker GB, Ballanyi K, Jhamandas JH. Fu W, et al. Among authors: jhamandas jh. Neuroscience. 2013 Oct 10;250:520-35. doi: 10.1016/j.neuroscience.2013.07.029. Epub 2013 Jul 20. Neuroscience. 2013. PMID: 23876319
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