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CD4-anchoring HIV-1 fusion inhibitor with enhanced potency and in vivo stability.
Ji C, Kopetzki E, Jekle A, Stubenrauch KG, Liu X, Zhang J, Rao E, Schlothauer T, Fischer S, Cammack N, Heilek G, Ries S, Sankuratri S. Ji C, et al. J Biol Chem. 2009 Feb 20;284(8):5175-85. doi: 10.1074/jbc.M808745200. Epub 2008 Dec 19. J Biol Chem. 2009. PMID: 19097993 Free article.
Previously, we have reported a CCR5 antibody-based bifunctional HIV-1 fusion inhibitor (BFFI) that was highly active in blocking R5 HIV-1 infection but was ineffective against X4 viruses infecting human PBMCs (Kopetzki, E., Jekle, A., Ji, C., Rao, E., Zhang, J., Fis …
Previously, we have reported a CCR5 antibody-based bifunctional HIV-1 fusion inhibitor (BFFI) that was highly active in blocking R5 HIV-1 in …
Novel CCR5 monoclonal antibodies with potent and broad-spectrum anti-HIV activities.
Ji C, Brandt M, Dioszegi M, Jekle A, Schwoerer S, Challand S, Zhang J, Chen Y, Zautke L, Achhammer G, Baehner M, Kroetz S, Heilek-Snyder G, Schumacher R, Cammack N, Sankuratri S. Ji C, et al. Antiviral Res. 2007 May;74(2):125-37. doi: 10.1016/j.antiviral.2006.11.003. Epub 2006 Dec 5. Antiviral Res. 2007. PMID: 17166600
4,144 results