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Ionotropic and metabotropic receptors, protein kinase A, protein kinase C, and Src contribute to C-fiber-induced ERK activation and cAMP response element-binding protein phosphorylation in dorsal horn neurons, leading to central sensitization.
Kawasaki Y, Kohno T, Zhuang ZY, Brenner GJ, Wang H, Van Der Meer C, Befort K, Woolf CJ, Ji RR. Kawasaki Y, et al. Among authors: ji rr. J Neurosci. 2004 Sep 22;24(38):8310-21. doi: 10.1523/JNEUROSCI.2396-04.2004. J Neurosci. 2004. PMID: 15385614 Free PMC article.
A peptide c-Jun N-terminal kinase (JNK) inhibitor blocks mechanical allodynia after spinal nerve ligation: respective roles of JNK activation in primary sensory neurons and spinal astrocytes for neuropathic pain development and maintenance.
Zhuang ZY, Wen YR, Zhang DR, Borsello T, Bonny C, Strichartz GR, Decosterd I, Ji RR. Zhuang ZY, et al. Among authors: ji rr. J Neurosci. 2006 Mar 29;26(13):3551-60. doi: 10.1523/JNEUROSCI.5290-05.2006. J Neurosci. 2006. PMID: 16571763 Free PMC article.
266 results