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Prodrugs of fluoro-substituted benzoates of EGC as tumor cellular proteasome inhibitors and apoptosis inducers.
Yu Z, Qin XL, Gu YY, Chen D, Cui QC, Jiang T, Wan SB, Dou QP. Yu Z, et al. Among authors: Jiang T. Int J Mol Sci. 2008 Jun;9(6):951-61. doi: 10.3390/ijms9060951. Epub 2008 Jun 2. Int J Mol Sci. 2008. PMID: 19325839 Free PMC article.
We report that the prodrug form of one F-EGCG analog exhibited greater potency than the previously reported peracetate of (-)-EGCG to inhibit proteasomal activity, suppress cell proliferation, and induce apoptosis in human leukemia Jurkat T cells, demonstrating the potential of these compounds to be developed into novel anti-cancer and cancer-preventive agents....
We report that the prodrug form of one F-EGCG analog exhibited greater potency than the previously reported peracetate of (-)-EGCG to inhibi …
The chemokine CXCL12 and its receptor CXCR4 promote glioma stem cell-mediated VEGF production and tumour angiogenesis via PI3K/AKT signalling.
Ping YF, Yao XH, Jiang JY, Zhao LT, Yu SC, Jiang T, Lin MC, Chen JH, Wang B, Zhang R, Cui YH, Qian C, Wang Jm, Bian XW. Ping YF, et al. Among authors: Jiang JY, Jiang T. J Pathol. 2011 Jul;224(3):344-54. doi: 10.1002/path.2908. Epub 2011 May 27. J Pathol. 2011. PMID: 21618540
Annexin 1 released by necrotic human glioblastoma cells stimulates tumor cell growth through the formyl peptide receptor 1.
Yang Y, Liu Y, Yao X, Ping Y, Jiang T, Liu Q, Xu S, Huang J, Mou H, Gong W, Chen K, Bian X, Wang JM. Yang Y, et al. Among authors: Jiang T. Am J Pathol. 2011 Sep;179(3):1504-12. doi: 10.1016/j.ajpath.2011.05.059. Epub 2011 Jul 22. Am J Pathol. 2011. PMID: 21782780 Free PMC article.
DKC1 serves as a potential prognostic biomarker for human clear cell renal cell carcinoma and promotes its proliferation, migration and invasion via the NF‑κB pathway.
Zhang M, Pan Y, Jiang R, Hou P, Shan H, Chen F, Jiang T, Bai J, Zheng J. Zhang M, et al. Among authors: Jiang R, Jiang T. Oncol Rep. 2018 Aug;40(2):968-978. doi: 10.3892/or.2018.6484. Epub 2018 Jun 11. Oncol Rep. 2018. PMID: 29901172
Inhibition of GKN2 Attenuates Acute Gastric Lesions Through the NLRP3 Inflammasome.
Zhang Z, Xue H, Dong Y, Hu J, Jiang T, Shi L, Du J. Zhang Z, et al. Among authors: Jiang T. Adv Wound Care (New Rochelle). 2020 May 1;9(5):219-232. doi: 10.1089/wound.2019.0957. Epub 2020 Mar 19. Adv Wound Care (New Rochelle). 2020. PMID: 32226647 Free PMC article.
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