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Year Number of Results
2018 5
2019 185
2020 10
2021 5
2022 4
2023 1
2024 3

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200 results

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Page 1
Metamaterial Lensing Devices.
Lv J, Zhou M, Gu Q, Jiang X, Ying Y, Si G. Lv J, et al. Molecules. 2019 Jul 4;24(13):2460. doi: 10.3390/molecules24132460. Molecules. 2019. PMID: 31277470 Free PMC article. Review.
Syndecan 1 is a critical mediator of macropinocytosis in pancreatic cancer.
Yao W, Rose JL, Wang W, Seth S, Jiang H, Taguchi A, Liu J, Yan L, Kapoor A, Hou P, Chen Z, Wang Q, Nezi L, Xu Z, Yao J, Hu B, Pettazzoni PF, Ho IL, Feng N, Ramamoorthy V, Jiang S, Deng P, Ma GJ, Den P, Tan Z, Zhang SX, Wang H, Wang YA, Deem AK, Fleming JB, Carugo A, Heffernan TP, Maitra A, Viale A, Ying H, Hanash S, DePinho RA, Draetta GF. Yao W, et al. Nature. 2019 Apr;568(7752):410-414. doi: 10.1038/s41586-019-1062-1. Epub 2019 Mar 27. Nature. 2019. PMID: 30918400 Free PMC article.
Thus, our study forges a mechanistic link between KRAS* signalling and a targetable molecule driving nutrient salvage pathways in PDAC and validates oncogene-driven surfaceome annotation as a strategy to identify cancer-specific vulnerabilities....
Thus, our study forges a mechanistic link between KRAS* signalling and a targetable molecule driving nutrient salvage pathways in PDA …
Fast and Efficient CRISPR/Cas9 Genome Editing In Vivo Enabled by Bioreducible Lipid and Messenger RNA Nanoparticles.
Liu J, Chang J, Jiang Y, Meng X, Sun T, Mao L, Xu Q, Wang M. Liu J, et al. Adv Mater. 2019 Aug;31(33):e1902575. doi: 10.1002/adma.201902575. Epub 2019 Jun 19. Adv Mater. 2019. PMID: 31215123 Free PMC article.
BAMEA-O16B, a lipid nanoparticle integrated with disulfide bonds, can efficiently deliver Cas9 mRNA and sgRNA into cells while releasing RNA in response to the reductive intracellular environment for genome editing as fast as 24 h post mRNA delivery. It is demonstrated tha …
BAMEA-O16B, a lipid nanoparticle integrated with disulfide bonds, can efficiently deliver Cas9 mRNA and sgRNA into cells while releasing RNA …
Safety and efficacy of losmapimod in facioscapulohumeral muscular dystrophy (ReDUX4): a randomised, double-blind, placebo-controlled phase 2b trial.
Tawil R, Wagner KR, Hamel JI, Leung DG, Statland JM, Wang LH, Genge A, Sacconi S, Lochmüller H, Reyes-Leiva D, Diaz-Manera J, Alonso-Perez J, Muelas N, Vilchez JJ, Pestronk A, Gibson S, Goyal NA, Hayward LJ, Johnson N, LoRusso S, Freimer M, Shieh PB, Subramony SH, van Engelen B, Kools J, Leinhard OD, Widholm P, Morabito C, Moxham CM, Cadavid D, Mellion ML, Odueyungbo A, Tracewell WG, Accorsi A, Ronco L, Gould RJ, Shoskes J, Rojas LA, Jiang JG. Tawil R, et al. Lancet Neurol. 2024 May;23(5):477-486. doi: 10.1016/S1474-4422(24)00073-5. Lancet Neurol. 2024. PMID: 38631764 Clinical Trial.
We aimed to assess the safety and efficacy of losmapimod (a small molecule that inhibits p38alpha MAPK, a regulator of DUX4 expression, and p38beta MAPK) for the treatment of facioscapulohumeral muscular dystrophy. ...The phase 2b trial is complete; an open-label extension …
We aimed to assess the safety and efficacy of losmapimod (a small molecule that inhibits p38alpha MAPK, a regulator of DUX4 expressio …
Metadevices with Potential Practical Applications.
Li Y, Lv J, Gu Q, Hu S, Li Z, Jiang X, Ying Y, Si G. Li Y, et al. Molecules. 2019 Jul 22;24(14):2651. doi: 10.3390/molecules24142651. Molecules. 2019. PMID: 31336634 Free PMC article. Review.
How much graphene in space?
Li Q, Li A, Jiang BW. Li Q, et al. Mon Not R Astron Soc. 2019 Dec;490(3):3875-3881. doi: 10.1093/mnras/stz2740. Epub 2019 Oct 3. Mon Not R Astron Soc. 2019. PMID: 31762496 Free PMC article.
The fact that the EELS dielectric functions are substantially smaller than that of SE naturally explains why a higher upper limit on the graphene abundance is derived with EELS. Inspired by the possible detection of C(24), a planar graphene sheet, in several Galactic and e …
The fact that the EELS dielectric functions are substantially smaller than that of SE naturally explains why a higher upper limit on the gra …
Frequent B7-H3 overexpression in craniopharyngioma.
Chen C, Wang Y, Zhong K, Jiang C, Wang L, Yuan Z, Nie C, Xu J, Guo G, Zhou L, Yang M, Tong A. Chen C, et al. Biochem Biophys Res Commun. 2019 Jun 25;514(2):379-385. doi: 10.1016/j.bbrc.2019.04.142. Epub 2019 Apr 28. Biochem Biophys Res Commun. 2019. PMID: 31043272
Craniopharyngiomas (CPs) are uncommon intracranial benign neoplasms that located in sellar/parasellar region with clinically challenging. B7-H3 is an immune checkpoint molecule highly expressed in many malignant tumors. In this study, we analyzed whether B7-H3 is expressed …
Craniopharyngiomas (CPs) are uncommon intracranial benign neoplasms that located in sellar/parasellar region with clinically challenging. B7 …
Anti-Cancer Activity of Porphyran and Carrageenan from Red Seaweeds.
Liu Z, Gao T, Yang Y, Meng F, Zhan F, Jiang Q, Sun X. Liu Z, et al. Molecules. 2019 Nov 25;24(23):4286. doi: 10.3390/molecules24234286. Molecules. 2019. PMID: 31775255 Free PMC article. Review.
The two polysaccharides have been found to have anti-cancer activity by improving immunity and targeting key apoptotic molecules and therefore deemed as potential chemotherapeutic or chemopreventive agents. ...
The two polysaccharides have been found to have anti-cancer activity by improving immunity and targeting key apoptotic molecules and …
Sinomenine attenuates pulmonary fibrosis by downregulating TGF-β1/Smad3, PI3K/Akt and NF-κB signaling pathways.
Yao F, Xu M, Dong L, Shen X, Shen Y, Jiang Y, Zhu T, Zhang C, Yu G. Yao F, et al. BMC Pulm Med. 2024 May 10;24(1):229. doi: 10.1186/s12890-024-03050-5. BMC Pulm Med. 2024. PMID: 38730387 Free PMC article.
BACKGROUND: Since COVID-19 became a global epidemic disease in 2019, pulmonary fibrosis (PF) has become more prevalent among persons with severe infections, with IPF being the most prevalent form. ...By administering various dosages of SIN and the TGF- receptor inhibitor S …
BACKGROUND: Since COVID-19 became a global epidemic disease in 2019, pulmonary fibrosis (PF) has become more prevalent among persons …
200 results