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The spike receptor-binding motif G496S substitution determines the replication fitness of SARS-CoV-2 Omicron sublineage.
Liang R, Ye ZW, Ong CP, Qin Z, Xie Y, Fan Y, Tang K, Poon VK, Chan CC, Yang X, Cao H, Wang K, Sun H, Hu B, Cai JP, Luo C, Chik KK, Chu H, Zheng Y, Yuen KY, Chan JF, Jin DY, Yuan S. Liang R, et al. Among authors: jin dy. Emerg Microbes Infect. 2022 Aug 9:1-20. doi: 10.1080/22221751.2022.2111977. Online ahead of print. Emerg Microbes Infect. 2022. PMID: 35943779 Free article.
Coronaviruses exploit a host cysteine-aspartic protease for replication.
Chu H, Hou Y, Yang D, Wen L, Shuai H, Yoon C, Shi J, Chai Y, Yuen TT, Hu B, Li C, Zhao X, Wang Y, Huang X, Lee KS, Cuiting L, Cai JP, Poon VK, Chan CC, Zhang AJ, Yuan S, Sit KY, Foo DC, Au WK, Wong KK, Zhou J, Kok KH, Jin DY, Chan JF, Yuen KY. Chu H, et al. Among authors: jin dy. Nature. 2022 Aug 3. doi: 10.1038/s41586-022-05148-4. Online ahead of print. Nature. 2022. PMID: 35922005
3,751 results