Jinek M - Search Results

1

Hakai is required for stabilization of core components of the m⁶A mRNA methylation machinery.

Bawankar P, Lence T, Paolantoni C, Haussmann IU, Kazlauskiene M, Jacob D, Heidelberger JB, Richter FM, Nallasivan MP, Morin V, Kreim N, Beli P, Helm M, Jinek M, Soller M, Roignant JY. Bawankar P, et al. Among authors: jinek m. Nat Commun. 2021 Jun 18;12(1):3778. doi: 10.1038/s41467-021-23892-5. Nat Commun. 2021. PMID: 34145251 Free PMC article.

2

PAM-Flexible Genome Editing with an Engineered Chimeric Cas9.

Koseki S, Hong L, Yudistyra V, Stan T, Tysinger E, Silverstein R, Kramme C, Amrani N, Savic N, Pacesa M, Rodriguez T, Ponnapati M, Jacobson J, Church G, Truant R, Jinek M, Kleinstiver B, Sontheimer E, Chatterjee P. Koseki S, et al. Among authors: jinek m. Res Sq [Preprint]. 2023 Mar 7:rs.3.rs-2625838. doi: 10.21203/rs.3.rs-2625838/v1. Res Sq. 2023. Update in: Nat Commun. 2023 Oct 4;14(1):6175. doi: 10.1038/s41467-023-41829-y. PMID: 36945419 Free PMC article. Updated. Preprint.

3

Targeted knock-in of NCF1 cDNA into the NCF2 locus leads to myeloid phenotypic correction of p47 ^phox -deficient chronic granulomatous disease.

Siow KM, Güngör M, Wrona D, Raimondi F, Pastukhov O, Tsapogas P, Menzi T, Schmitz M, Kulcsár PI, Schwank G, Schulz A, Jinek M, Modlich U, Siler U, Reichenbach J. Siow KM, et al. Among authors: jinek m. Mol Ther Nucleic Acids. 2024 May 24;35(3):102229. doi: 10.1016/j.omtn.2024.102229. eCollection 2024 Sep 10. Mol Ther Nucleic Acids. 2024. PMID: 38952440 Free PMC article.

4

Massively parallel analysis of single-molecule dynamics on next-generation sequencing chips.

Aguirre Rivera J, Mao G, Sabantsev A, Panfilov M, Hou Q, Lindell M, Chanez C, Ritort F, Jinek M, Deindl S. Aguirre Rivera J, et al. Among authors: jinek m. Science. 2024 Aug 23;385(6711):892-898. doi: 10.1126/science.adn5371. Epub 2024 Aug 22. Science. 2024. PMID: 39172826

5

Structural basis for Cas9 off-target activity.

Pacesa M, Lin CH, Cléry A, Saha A, Arantes PR, Bargsten K, Irby MJ, Allain FH, Palermo G, Cameron P, Donohoue PD, Jinek M. Pacesa M, et al. Among authors: jinek m. Cell. 2022 Oct 27;185(22):4067-4081.e21. doi: 10.1016/j.cell.2022.09.026. Cell. 2022. PMID: 36306733 Free PMC article.

6

Mechanistic determinants and dynamics of cA6 synthesis in type III CRISPR-Cas effector complexes.

Jungfer K, Moravčík Š, Garcia-Doval C, Knörlein A, Hall J, Jinek M. Jungfer K, et al. Among authors: jinek m. Nucleic Acids Res. 2025 Jan 11;53(2):gkae1277. doi: 10.1093/nar/gkae1277. Nucleic Acids Res. 2025. PMID: 39817514 Free PMC article.

7

A three-dimensional view of the molecular machinery of RNA interference.

Jinek M, Doudna JA. Jinek M, et al. Nature. 2009 Jan 22;457(7228):405-12. doi: 10.1038/nature07755. Nature. 2009. PMID: 19158786 Review.

8

Structural insights into the human GW182-PABC interaction in microRNA-mediated deadenylation.

Jinek M, Fabian MR, Coyle SM, Sonenberg N, Doudna JA. Jinek M, et al. Nat Struct Mol Biol. 2010 Feb;17(2):238-40. doi: 10.1038/nsmb.1768. Epub 2010 Jan 24. Nat Struct Mol Biol. 2010. PMID: 20098421 Free PMC article.

9

Structural basis of PAM-dependent target DNA recognition by the Cas9 endonuclease.

Anders C, Niewoehner O, Duerst A, Jinek M. Anders C, et al. Among authors: jinek m. Nature. 2014 Sep 25;513(7519):569-73. doi: 10.1038/nature13579. Epub 2014 Jul 27. Nature. 2014. PMID: 25079318 Free PMC article.

10

Structural insights into the molecular mechanism of the m(6)A writer complex.

Śledź P, Jinek M. Śledź P, et al. Among authors: jinek m. Elife. 2016 Sep 14;5:e18434. doi: 10.7554/eLife.18434. Elife. 2016. PMID: 27627798 Free PMC article.

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