Jing Q - Search Results

1

Inhibitor Bound Crystal Structures of Bacterial Nitric Oxide Synthase.

Holden JK, Dejam D, Lewis MC, Huang H, Kang S, Jing Q, Xue F, Silverman RB, Poulos TL. Holden JK, et al. Among authors: jing q. Biochemistry. 2015 Jul 7;54(26):4075-82. doi: 10.1021/acs.biochem.5b00431. Epub 2015 Jun 23. Biochemistry. 2015. PMID: 26062720 Free PMC article.

2

Selective monocationic inhibitors of neuronal nitric oxide synthase. Binding mode insights from molecular dynamics simulations.

Huang H, Ji H, Li H, Jing Q, Labby KJ, Martásek P, Roman LJ, Poulos TL, Silverman RB. Huang H, et al. Among authors: jing q. J Am Chem Soc. 2012 Jul 18;134(28):11559-72. doi: 10.1021/ja302269r. Epub 2012 Jul 10. J Am Chem Soc. 2012. PMID: 22731813 Free PMC article.

3

In search of potent and selective inhibitors of neuronal nitric oxide synthase with more simple structures.

Jing Q, Li H, Fang J, Roman LJ, Martásek P, Poulos TL, Silverman RB. Jing Q, et al. Bioorg Med Chem. 2013 Sep 1;21(17):5323-31. doi: 10.1016/j.bmc.2013.06.014. Epub 2013 Jun 15. Bioorg Med Chem. 2013. PMID: 23867386 Free PMC article.

4

Chiral linkers to improve selectivity of double-headed neuronal nitric oxide synthase inhibitors.

Jing Q, Li H, Chreifi G, Roman LJ, Martásek P, Poulos TL, Silverman RB. Jing Q, et al. Bioorg Med Chem Lett. 2013 Oct 15;23(20):5674-9. doi: 10.1016/j.bmcl.2013.08.034. Epub 2013 Aug 14. Bioorg Med Chem Lett. 2013. PMID: 23993333 Free PMC article.

5

Structural and biological studies on bacterial nitric oxide synthase inhibitors.

Holden JK, Li H, Jing Q, Kang S, Richo J, Silverman RB, Poulos TL. Holden JK, et al. Among authors: jing q. Proc Natl Acad Sci U S A. 2013 Nov 5;110(45):18127-31. doi: 10.1073/pnas.1314080110. Epub 2013 Oct 21. Proc Natl Acad Sci U S A. 2013. PMID: 24145412 Free PMC article.

6

An Accessible Chiral Linker to Enhance Potency and Selectivity of Neuronal Nitric Oxide Synthase Inhibitors.

Jing Q, Li H, Roman LJ, Martásek P, Poulos TL, Silverman RB. Jing Q, et al. ACS Med Chem Lett. 2014 Jan 9;5(1):56-60. doi: 10.1021/ml400381s. ACS Med Chem Lett. 2014. PMID: 24660051 Free PMC article.

7

The mobility of a conserved tyrosine residue controls isoform-dependent enzyme-inhibitor interactions in nitric oxide synthases.

Li H, Jamal J, Delker S, Plaza C, Ji H, Jing Q, Huang H, Kang S, Silverman RB, Poulos TL. Li H, et al. Among authors: jing q. Biochemistry. 2014 Aug 19;53(32):5272-9. doi: 10.1021/bi500561h. Epub 2014 Aug 11. Biochemistry. 2014. PMID: 25089924 Free PMC article.

8

Combination of chiral linkers with thiophenecarboximidamide heads to improve the selectivity of inhibitors of neuronal nitric oxide synthase.

Jing Q, Li H, Roman LJ, Martásek P, Poulos TL, Silverman RB. Jing Q, et al. Bioorg Med Chem Lett. 2014 Sep 15;24(18):4504-4510. doi: 10.1016/j.bmcl.2014.07.079. Epub 2014 Aug 12. Bioorg Med Chem Lett. 2014. PMID: 25149509 Free PMC article.

9

Structures of human constitutive nitric oxide synthases.

Li H, Jamal J, Plaza C, Pineda SH, Chreifi G, Jing Q, Cinelli MA, Silverman RB, Poulos TL. Li H, et al. Among authors: jing q. Acta Crystallogr D Biol Crystallogr. 2014 Oct;70(Pt 10):2667-74. doi: 10.1107/S1399004714017064. Epub 2014 Sep 27. Acta Crystallogr D Biol Crystallogr. 2014. PMID: 25286850 Free PMC article.

10

Acid-Facilitated Debenzylation of N-Boc, N-Benzyl Double Protected 2-Aminopyridinomethylpyrrolidine Derivatives.

Ji H, Jing Q, Huang J, Silverman RB. Ji H, et al. Among authors: jing q. Tetrahedron. 2012 Feb 4;68(5):1359-1366. doi: 10.1016/j.tet.2011.12.013. Epub 2011 Dec 13. Tetrahedron. 2012. PMID: 22639474 Free PMC article.

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