Jo H - Search Results

1

Entry from the Lipid Bilayer: A Possible Pathway for Inhibition of a Peptide G Protein-Coupled Receptor by a Lipophilic Small Molecule.

Bokoch MP, Jo H, Valcourt JR, Srinivasan Y, Pan AC, Capponi S, Grabe M, Dror RO, Shaw DE, DeGrado WF, Coughlin SR. Bokoch MP, et al. Among authors: jo h. Biochemistry. 2018 Oct 2;57(39):5748-5758. doi: 10.1021/acs.biochem.8b00577. Epub 2018 Aug 27. Biochemistry. 2018. PMID: 30102523 Free PMC article.

2

Discovery of potent small-molecule inhibitors of multidrug-resistant Plasmodium falciparum using a novel miniaturized high-throughput luciferase-based assay.

Lucumi E, Darling C, Jo H, Napper AD, Chandramohanadas R, Fisher N, Shone AE, Jing H, Ward SA, Biagini GA, DeGrado WF, Diamond SL, Greenbaum DC. Lucumi E, et al. Among authors: jo h. Antimicrob Agents Chemother. 2010 Sep;54(9):3597-604. doi: 10.1128/AAC.00431-10. Epub 2010 Jun 14. Antimicrob Agents Chemother. 2010. PMID: 20547797 Free PMC article.

3

Selective incorporation of nitrile-based infrared probes into proteins via cysteine alkylation.

Jo H, Culik RM, Korendovych IV, Degrado WF, Gai F. Jo H, et al. Biochemistry. 2010 Dec 14;49(49):10354-6. doi: 10.1021/bi101711a. Epub 2010 Nov 17. Biochemistry. 2010. PMID: 21077670 Free PMC article.

4

Affinity of talin-1 for the β3-integrin cytosolic domain is modulated by its phospholipid bilayer environment.

Moore DT, Nygren P, Jo H, Boesze-Battaglia K, Bennett JS, DeGrado WF. Moore DT, et al. Among authors: jo h. Proc Natl Acad Sci U S A. 2012 Jan 17;109(3):793-8. doi: 10.1073/pnas.1117220108. Epub 2011 Dec 30. Proc Natl Acad Sci U S A. 2012. PMID: 22210111 Free PMC article.

5

Using thioamides to site-specifically interrogate the dynamics of hydrogen bond formation in β-sheet folding.

Culik RM, Jo H, DeGrado WF, Gai F. Culik RM, et al. Among authors: jo h. J Am Chem Soc. 2012 May 16;134(19):8026-9. doi: 10.1021/ja301681v. Epub 2012 May 2. J Am Chem Soc. 2012. PMID: 22540162 Free PMC article.

6

Development of α-helical calpain probes by mimicking a natural protein-protein interaction.

Jo H, Meinhardt N, Wu Y, Kulkarni S, Hu X, Low KE, Davies PL, DeGrado WF, Greenbaum DC. Jo H, et al. J Am Chem Soc. 2012 Oct 24;134(42):17704-13. doi: 10.1021/ja307599z. Epub 2012 Oct 11. J Am Chem Soc. 2012. PMID: 22998171 Free PMC article.

7

Alteration of the oxygen-dependent reactivity of de novo Due Ferri proteins.

Reig AJ, Pires MM, Snyder RA, Wu Y, Jo H, Kulp DW, Butch SE, Calhoun JR, Szyperski T, Solomon EI, DeGrado WF. Reig AJ, et al. Among authors: jo h. Nat Chem. 2012 Nov;4(11):900-6. doi: 10.1038/nchem.1454. Epub 2012 Sep 23. Nat Chem. 2012. PMID: 23089864 Free PMC article.

8

Discovery of novel dual inhibitors of the wild-type and the most prevalent drug-resistant mutant, S31N, of the M2 proton channel from influenza A virus.

Wang J, Ma C, Wang J, Jo H, Canturk B, Fiorin G, Pinto LH, Lamb RA, Klein ML, DeGrado WF. Wang J, et al. Among authors: jo h. J Med Chem. 2013 Apr 11;56(7):2804-12. doi: 10.1021/jm301538e. Epub 2013 Mar 27. J Med Chem. 2013. PMID: 23437766 Free PMC article.

9

Assessment of local friction in protein folding dynamics using a helix cross-linker.

Markiewicz BN, Jo H, Culik RM, DeGrado WF, Gai F. Markiewicz BN, et al. Among authors: jo h. J Phys Chem B. 2013 Nov 27;117(47):14688-96. doi: 10.1021/jp409334h. Epub 2013 Nov 18. J Phys Chem B. 2013. PMID: 24205975 Free PMC article.

10

Flipping in the pore: discovery of dual inhibitors that bind in different orientations to the wild-type versus the amantadine-resistant S31N mutant of the influenza A virus M2 proton channel.

Wu Y, Canturk B, Jo H, Ma C, Gianti E, Klein ML, Pinto LH, Lamb RA, Fiorin G, Wang J, DeGrado WF. Wu Y, et al. Among authors: jo h. J Am Chem Soc. 2014 Dec 31;136(52):17987-95. doi: 10.1021/ja508461m. Epub 2014 Dec 18. J Am Chem Soc. 2014. PMID: 25470189 Free PMC article.

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