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Tumor-infiltrating immune cells and prognosis: the potential link between conventional cancer therapy and immunity.

Jochems C, Schlom J. Jochems C, et al. Exp Biol Med (Maywood). 2011 May 1;236(5):567-79. doi: 10.1258/ebm.2011.011007. Epub 2011 Apr 12. Exp Biol Med (Maywood). 2011. PMID: 21486861 Free PMC article. Review.

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Maturation of human dendritic cells with Saccharomyces cerevisiae (yeast) reduces the number and function of regulatory T cells and enhances the ratio of antigen-specific effectors to regulatory T cells.

Cereda V, Vergati M, Huen NY, di Bari MG, Jochems C, Intrivici C, Gulley JL, Apelian D, Schlom J, Tsang KY. Cereda V, et al. Among authors: jochems c. Vaccine. 2011 Jul 12;29(31):4992-9. doi: 10.1016/j.vaccine.2011.04.101. Epub 2011 May 11. Vaccine. 2011. PMID: 21569810 Free PMC article.

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A pilot study of MUC-1/CEA/TRICOM poxviral-based vaccine in patients with metastatic breast and ovarian cancer.

Mohebtash M, Tsang KY, Madan RA, Huen NY, Poole DJ, Jochems C, Jones J, Ferrara T, Heery CR, Arlen PM, Steinberg SM, Pazdur M, Rauckhorst M, Jones EC, Dahut WL, Schlom J, Gulley JL. Mohebtash M, et al. Among authors: jochems c. Clin Cancer Res. 2011 Nov 15;17(22):7164-73. doi: 10.1158/1078-0432.CCR-11-0649. Epub 2011 Nov 8. Clin Cancer Res. 2011. PMID: 22068656 Free PMC article.

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Elevated serum soluble CD40 ligand in cancer patients may play an immunosuppressive role.

Huang J, Jochems C, Talaie T, Anderson A, Jales A, Tsang KY, Madan RA, Gulley JL, Schlom J. Huang J, et al. Among authors: jochems c. Blood. 2012 Oct 11;120(15):3030-8. doi: 10.1182/blood-2012-05-427799. Epub 2012 Aug 28. Blood. 2012. PMID: 22932804 Free PMC article.

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Up-regulation of proliferative and migratory genes in regulatory T cells from patients with metastatic castration-resistant prostate cancer.

Huen NY, Pang AL, Tucker JA, Lee TL, Vergati M, Jochems C, Intrivici C, Cereda V, Chan WY, Rennert OM, Madan RA, Gulley JL, Schlom J, Tsang KY. Huen NY, et al. Among authors: jochems c. Int J Cancer. 2013 Jul 15;133(2):373-82. doi: 10.1002/ijc.28026. Epub 2013 Feb 12. Int J Cancer. 2013. PMID: 23319273 Free PMC article.

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The role of soluble CD40L in immunosuppression.

Schlom J, Jochems C, Gulley JL, Huang J. Schlom J, et al. Among authors: jochems c. Oncoimmunology. 2013 Jan 1;2(1):e22546. doi: 10.4161/onci.22546. Oncoimmunology. 2013. PMID: 23483661 Free PMC article.

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Soluble CD27-pool in humans may contribute to T cell activation and tumor immunity.

Huang J, Jochems C, Anderson AM, Talaie T, Jales A, Madan RA, Hodge JW, Tsang KY, Liewehr DJ, Steinberg SM, Gulley JL, Schlom J. Huang J, et al. Among authors: jochems c. J Immunol. 2013 Jun 15;190(12):6250-8. doi: 10.4049/jimmunol.1300022. Epub 2013 May 15. J Immunol. 2013. PMID: 23677477 Free PMC article.

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Effect of talactoferrin alfa on the immune system in adults with non-small cell lung cancer.

Madan RA, Tsang KY, Bilusic M, Vergati M, Poole DJ, Jochems C, Tucker JA, Schlom J, Giaccone G, Gulley JL. Madan RA, et al. Among authors: jochems c. Oncologist. 2013;18(7):821-2. doi: 10.1634/theoncologist.2013-0199. Epub 2013 Jul 11. Oncologist. 2013. PMID: 23847257 Free PMC article.

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Immunotherapy: shifting the balance of cell-mediated immunity and suppression in human prostate cancer.

Tucker JA, Jochems C, Gulley JL, Schlom J, Tsang KY. Tucker JA, et al. Among authors: jochems c. Cancers (Basel). 2012 Dec 11;4(4):1333-48. doi: 10.3390/cancers4041333. Cancers (Basel). 2012. PMID: 24213509 Free PMC article.

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Phase I trial of a recombinant yeast-CEA vaccine (GI-6207) in adults with metastatic CEA-expressing carcinoma.

Bilusic M, Heery CR, Arlen PM, Rauckhorst M, Apelian D, Tsang KY, Tucker JA, Jochems C, Schlom J, Gulley JL, Madan RA. Bilusic M, et al. Among authors: jochems c. Cancer Immunol Immunother. 2014 Mar;63(3):225-34. doi: 10.1007/s00262-013-1505-8. Epub 2013 Dec 7. Cancer Immunol Immunother. 2014. PMID: 24327292 Free PMC article. Clinical Trial.

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