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WT1 proteins: functions in growth and differentiation.
Scharnhorst V, van der Eb AJ, Jochemsen AG. Scharnhorst V, et al. Among authors: jochemsen ag. Gene. 2001 Aug 8;273(2):141-61. doi: 10.1016/s0378-1119(01)00593-5. Gene. 2001. PMID: 11595161 Review.
Targeting Mdmx to treat breast cancers with wild-type p53.
Haupt S, Buckley D, Pang JM, Panimaya J, Paul PJ, Gamell C, Takano EA, Lee YY, Hiddingh S, Rogers TM, Teunisse AF, Herold MJ, Marine JC, Fox SB, Jochemsen A, Haupt Y. Haupt S, et al. Among authors: jochemsen a. Cell Death Dis. 2015 Jul 16;6(7):e1821. doi: 10.1038/cddis.2015.173. Cell Death Dis. 2015. PMID: 26181202 Free PMC article.
Synergistic growth inhibition based on small-molecule p53 activation as treatment for intraocular melanoma.
de Lange J, Ly LV, Lodder K, Verlaan-de Vries M, Teunisse AF, Jager MJ, Jochemsen AG. de Lange J, et al. Among authors: jochemsen ag. Oncogene. 2012 Mar 1;31(9):1105-16. doi: 10.1038/onc.2011.309. Epub 2011 Jul 18. Oncogene. 2012. PMID: 21765463
Mdm2, but not Mdm4, protects terminally differentiated smooth muscle cells from p53-mediated caspase-3-independent cell death.
Boesten LS, Zadelaar SM, De Clercq S, Francoz S, van Nieuwkoop A, Biessen EA, Hofmann F, Feil S, Feil R, Jochemsen AG, Zurcher C, Havekes LM, van Vlijmen BJ, Marine JC. Boesten LS, et al. Among authors: jochemsen ag. Cell Death Differ. 2006 Dec;13(12):2089-98. doi: 10.1038/sj.cdd.4401973. Epub 2006 May 26. Cell Death Differ. 2006. PMID: 16729027
Hdmx and Mdm2 can repress transcription activation by p53 but not by p63.
Little NA, Jochemsen AG. Little NA, et al. Among authors: jochemsen ag. Oncogene. 2001 Jul 27;20(33):4576-80. doi: 10.1038/sj.onc.1204615. Oncogene. 2001. PMID: 11494153
Aberrant expression of HDMX proteins in tumor cells correlates with wild-type p53.
Ramos YF, Stad R, Attema J, Peltenburg LT, van der Eb AJ, Jochemsen AG. Ramos YF, et al. Among authors: jochemsen ag. Cancer Res. 2001 Mar 1;61(5):1839-42. Cancer Res. 2001. PMID: 11280734
Human chromosome 11 suppresses the tumorigenicity of adenovirus transformed baby rat kidney cells: involvement of the Wilms' tumor 1 gene.
Menke AL, van Ham RC, Sonneveld E, Shvarts A, Stanbridge EJ, Miyagawa K, van der Eb AJ, Jochemsen AG. Menke AL, et al. Among authors: jochemsen ag. Int J Cancer. 1995 Sep 27;63(1):76-85. doi: 10.1002/ijc.2910630115. Int J Cancer. 1995. PMID: 7558457
Distinct modulation of p53 activity in transcription and cell-cycle regulation by the large (54 kDa) and small (21 kDa) adenovirus E1B proteins.
Steegenga WT, Van Laar T, Shvarts A, Terleth C, Van der Eb AJ, Jochemsen AG. Steegenga WT, et al. Among authors: jochemsen ag. Virology. 1995 Oct 1;212(2):543-54. doi: 10.1006/viro.1995.1512. Virology. 1995. PMID: 7571424
Mutational analysis of fibrillarin and its mobility in living human cells.
Snaar S, Wiesmeijer K, Jochemsen AG, Tanke HJ, Dirks RW. Snaar S, et al. Among authors: jochemsen ag. J Cell Biol. 2000 Oct 30;151(3):653-62. doi: 10.1083/jcb.151.3.653. J Cell Biol. 2000. PMID: 11062265 Free PMC article.
Distinct regulation of p53 and p73 activity by adenovirus E1A, E1B, and E4orf6 proteins.
Steegenga WT, Shvarts A, Riteco N, Bos JL, Jochemsen AG. Steegenga WT, et al. Among authors: jochemsen ag. Mol Cell Biol. 1999 May;19(5):3885-94. doi: 10.1128/mcb.19.5.3885. Mol Cell Biol. 1999. PMID: 10207112 Free PMC article.
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