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Mdmx as an essential regulator of p53 activity.
Marine JC, Jochemsen AG. Marine JC, et al. Among authors: jochemsen ag. Biochem Biophys Res Commun. 2005 Jun 10;331(3):750-60. doi: 10.1016/j.bbrc.2005.03.151. Biochem Biophys Res Commun. 2005. PMID: 15865931 Review.
MDM4 is a key therapeutic target in cutaneous melanoma.
Gembarska A, Luciani F, Fedele C, Russell EA, Dewaele M, Villar S, Zwolinska A, Haupt S, de Lange J, Yip D, Goydos J, Haigh JJ, Haupt Y, Larue L, Jochemsen A, Shi H, Moriceau G, Lo RS, Ghanem G, Shackleton M, Bernal F, Marine JC. Gembarska A, et al. Nat Med. 2012 Aug;18(8):1239-47. doi: 10.1038/nm.2863. Epub 2012 Jul 22. Nat Med. 2012. PMID: 22820643 Free PMC article.
MDM4 is a rational target for treating breast cancers with mutant p53.
Miranda PJ, Buckley D, Raghu D, Pang JB, Takano EA, Vijayakumaran R, Teunisse AF, Posner A, Procter T, Herold MJ, Gamell C, Marine JC, Fox SB, Jochemsen A, Haupt S, Haupt Y. Miranda PJ, et al. J Pathol. 2017 Apr;241(5):661-670. doi: 10.1002/path.4877. Epub 2017 Mar 1. J Pathol. 2017. PMID: 28097652
Mdmx and Mdm2: brothers in arms?
Marine JC, Jochemsen AG. Marine JC, et al. Among authors: jochemsen ag. Cell Cycle. 2004 Jul;3(7):900-4. Epub 2004 Jul 2. Cell Cycle. 2004. PMID: 15254433 Review.
Critical role for a central part of Mdm2 in the ubiquitylation of p53.
Meulmeester E, Frenk R, Stad R, de Graaf P, Marine JC, Vousden KH, Jochemsen AG. Meulmeester E, et al. Among authors: jochemsen ag. Mol Cell Biol. 2003 Jul;23(14):4929-38. doi: 10.1128/MCB.23.14.4929-4938.2003. Mol Cell Biol. 2003. PMID: 12832478 Free PMC article.
The long non-coding RNA SAMMSON is essential for uveal melanoma cell survival.
Dewaele S, Delhaye L, De Paepe B, de Bony EJ, De Wilde J, Vanderheyden K, Anckaert J, Yigit N, Nuytens J, Vanden Eynde E, Smet J, Verschoore M, Nemati F, Decaudin D, Rodrigues M, Zhao P, Jochemsen A, Leucci E, Vandesompele J, Van Dorpe J, Marine JC, Van Coster R, Eyckerman S, Mestdagh P. Dewaele S, et al. Oncogene. 2022 Jan;41(1):15-25. doi: 10.1038/s41388-021-02006-x. Epub 2021 Sep 10. Oncogene. 2022. PMID: 34508176 Free PMC article.
133 results