Abstract
1,1, 1-trichloroéthane is derived from carbon tetrachloride and has been widely used as an industrial solvent since 1954, because of its supposed lack of toxicity. However, several cases of central nervous system toxicity and heart disorders due to intoxication by 1,1, 1-trichloroéthane have been reported. Cases of liver injury are infrequent, with less than 10 cases, unlike 1,1, 2-trichloroéthane that it replaced. We report a case of hepatotoxicity probably due to 1,1, 1-trichloroéthane exposure, characterized by an original pathologic feature of chronic active hepatitis.
Publication types
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Case Reports
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Comparative Study
MeSH terms
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Adult
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Biopsy
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Chemical and Drug Induced Liver Injury / diagnosis
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Chemical and Drug Induced Liver Injury / etiology*
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Chemical and Drug Induced Liver Injury / pathology
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Female
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Hepatitis, Chronic / diagnosis
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Hepatitis, Chronic / etiology*
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Hepatitis, Chronic / pathology
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Humans
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Liver / pathology
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Occupational Diseases / chemically induced*
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Occupational Diseases / diagnosis
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Occupational Diseases / pathology
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Occupational Exposure / adverse effects*
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Solvents / poisoning*
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Time Factors
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Trichloroethanes / poisoning*
Substances
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Solvents
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Trichloroethanes
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1,1,1-trichloroethane