Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

My NCBI Filters
Text availability
Article attribute
Article type
Publication date

Search Results

48 results
Filters applied: . Clear all Results are displayed in a computed author sort order. Results by year timeline is unavailable
Page 1
Structural basis for understanding oncogenic p53 mutations and designing rescue drugs.
Joerger AC, Ang HC, Fersht AR. Joerger AC, et al. Proc Natl Acad Sci U S A. 2006 Oct 10;103(41):15056-61. doi: 10.1073/pnas.0607286103. Epub 2006 Oct 2. Proc Natl Acad Sci U S A. 2006. PMID: 17015838 Free PMC article.
Mimicking natural evolution in vitro: an N-acetylneuraminate lyase mutant with an increased dihydrodipicolinate synthase activity.
Joerger AC, Mayer S, Fersht AR. Joerger AC, et al. Proc Natl Acad Sci U S A. 2003 May 13;100(10):5694-9. doi: 10.1073/pnas.0531477100. Epub 2003 Apr 23. Proc Natl Acad Sci U S A. 2003. PMID: 12711733 Free PMC article.
Crystal structure of a superstable mutant of human p53 core domain. Insights into the mechanism of rescuing oncogenic mutations.
Joerger AC, Allen MD, Fersht AR. Joerger AC, et al. J Biol Chem. 2004 Jan 9;279(2):1291-6. doi: 10.1074/jbc.M309732200. Epub 2003 Oct 8. J Biol Chem. 2004. PMID: 14534297
Structures of p53 cancer mutants and mechanism of rescue by second-site suppressor mutations.
Joerger AC, Ang HC, Veprintsev DB, Blair CM, Fersht AR. Joerger AC, et al. J Biol Chem. 2005 Apr 22;280(16):16030-7. doi: 10.1074/jbc.M500179200. Epub 2005 Feb 9. J Biol Chem. 2005. PMID: 15703170
Effects of common cancer mutations on stability and DNA binding of full-length p53 compared with isolated core domains.
Ang HC, Joerger AC, Mayer S, Fersht AR. Ang HC, et al. Among authors: joerger ac. J Biol Chem. 2006 Aug 4;281(31):21934-41. doi: 10.1074/jbc.M604209200. Epub 2006 Jun 5. J Biol Chem. 2006. PMID: 16754663
Structure-function-rescue: the diverse nature of common p53 cancer mutants.
Joerger AC, Fersht AR. Joerger AC, et al. Oncogene. 2007 Apr 2;26(15):2226-42. doi: 10.1038/sj.onc.1210291. Oncogene. 2007. PMID: 17401432 Review.
Structural biology of the tumor suppressor p53 and cancer-associated mutants.
Joerger AC, Fersht AR. Joerger AC, et al. Adv Cancer Res. 2007;97:1-23. doi: 10.1016/S0065-230X(06)97001-8. Adv Cancer Res. 2007. PMID: 17419939 Review.
Correlation of levels of folded recombinant p53 in escherichia coli with thermodynamic stability in vitro.
Mayer S, RĂ¼diger S, Ang HC, Joerger AC, Fersht AR. Mayer S, et al. Among authors: joerger ac. J Mol Biol. 2007 Sep 7;372(1):268-76. doi: 10.1016/j.jmb.2007.06.044. Epub 2007 Jun 22. J Mol Biol. 2007. PMID: 17631895
Structural biology of the tumor suppressor p53.
Joerger AC, Fersht AR. Joerger AC, et al. Annu Rev Biochem. 2008;77:557-82. doi: 10.1146/annurev.biochem.77.060806.091238. Annu Rev Biochem. 2008. PMID: 18410249 Review.
Targeted rescue of a destabilized mutant of p53 by an in silico screened drug.
Boeckler FM, Joerger AC, Jaggi G, Rutherford TJ, Veprintsev DB, Fersht AR. Boeckler FM, et al. Among authors: joerger ac. Proc Natl Acad Sci U S A. 2008 Jul 29;105(30):10360-5. doi: 10.1073/pnas.0805326105. Epub 2008 Jul 23. Proc Natl Acad Sci U S A. 2008. PMID: 18650397 Free PMC article.
48 results
You have reached the last page of results. A maximum of 10,000 results are available.
Jump to page
Feedback