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Platinum-based inhibitors of amyloid-beta as therapeutic agents for Alzheimer's disease.
Barnham KJ, Kenche VB, Ciccotosto GD, Smith DP, Tew DJ, Liu X, Perez K, Cranston GA, Johanssen TJ, Volitakis I, Bush AI, Masters CL, White AR, Smith JP, Cherny RA, Cappai R. Barnham KJ, et al. Among authors: johanssen tj. Proc Natl Acad Sci U S A. 2008 May 13;105(19):6813-8. doi: 10.1073/pnas.0800712105. Epub 2008 May 7. Proc Natl Acad Sci U S A. 2008. PMID: 18463291 Free PMC article.
Stereospecific interactions are necessary for Alzheimer disease amyloid-β toxicity.
Ciccotosto GD, Tew DJ, Drew SC, Smith DG, Johanssen T, Lal V, Lau TL, Perez K, Curtain CC, Wade JD, Separovic F, Masters CL, Smith JP, Barnham KJ, Cappai R. Ciccotosto GD, et al. Neurobiol Aging. 2011 Feb;32(2):235-48. doi: 10.1016/j.neurobiolaging.2009.02.018. Epub 2009 Mar 25. Neurobiol Aging. 2011. PMID: 19324459
Iron-export ferroxidase activity of β-amyloid precursor protein is inhibited by zinc in Alzheimer's disease.
Duce JA, Tsatsanis A, Cater MA, James SA, Robb E, Wikhe K, Leong SL, Perez K, Johanssen T, Greenough MA, Cho HH, Galatis D, Moir RD, Masters CL, McLean C, Tanzi RE, Cappai R, Barnham KJ, Ciccotosto GD, Rogers JT, Bush AI. Duce JA, et al. Cell. 2010 Sep 17;142(6):857-67. doi: 10.1016/j.cell.2010.08.014. Cell. 2010. PMID: 20817278 Free PMC article.