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Page 1
C-terminal peptides modelling constitutive PrPC processing demonstrate ameliorated toxicity predisposition consequent to α-cleavage.
Johanssen VA, Johanssen T, Masters CL, Hill AF, Barnham KJ, Collins SJ. Johanssen VA, et al. Biochem J. 2014 Apr 1;459(1):103-15. doi: 10.1042/BJ20131378. Biochem J. 2014. PMID: 24438129
Generating recombinant C-terminal prion protein fragments of exact native sequence.
Johanssen VA, Barnham KJ, Masters CL, Hill AF, Collins SJ. Johanssen VA, et al. Neurochem Int. 2012 Feb;60(3):318-26. doi: 10.1016/j.neuint.2011.12.006. Epub 2011 Dec 17. Neurochem Int. 2012. PMID: 22197912
Glycosaminoglycan sulfation determines the biochemical properties of prion protein aggregates.
Ellett LJ, Coleman BM, Shambrook MC, Johanssen VA, Collins SJ, Masters CL, Hill AF, Lawson VA. Ellett LJ, et al. Among authors: johanssen va. Glycobiology. 2015 Jul;25(7):745-55. doi: 10.1093/glycob/cwv014. Epub 2015 Feb 20. Glycobiology. 2015. PMID: 25701659
Prion protein "gamma-cleavage": characterizing a novel endoproteolytic processing event.
Lewis V, Johanssen VA, Crouch PJ, Klug GM, Hooper NM, Collins SJ. Lewis V, et al. Among authors: johanssen va. Cell Mol Life Sci. 2016 Feb;73(3):667-83. doi: 10.1007/s00018-015-2022-z. Epub 2015 Aug 23. Cell Mol Life Sci. 2016. PMID: 26298290
Analysis of Prion Protein Conformation Using Circular Dichroism Spectroscopy.
Ellett LJ, Johanssen VA. Ellett LJ, et al. Among authors: johanssen va. Methods Mol Biol. 2017;1658:27-34. doi: 10.1007/978-1-4939-7244-9_3. Methods Mol Biol. 2017. PMID: 28861780
Unusual clinical and molecular-pathological profile of gerstmann-Sträussler-Scheinker disease associated with a novel PRNP mutation (V176G).
Simpson M, Johanssen V, Boyd A, Klug G, Masters CL, Li QX, Pamphlett R, McLean C, Lewis V, Collins SJ. Simpson M, et al. JAMA Neurol. 2013 Sep 1;70(9):1180-5. doi: 10.1001/jamaneurol.2013.165. JAMA Neurol. 2013. PMID: 23857164
Correction to: Amyloid Precursor Protein Mediates Neuronal Protection from Rotenone Toxicity.
Cimdins K, Waugh HS, Chrysostomou V, Lopez Sanchez MIG, Johanssen VA, Cook MJ, Crowston JG, Hill AF, Duce JA, Bush AI, Trounce IA. Cimdins K, et al. Among authors: johanssen va. Mol Neurobiol. 2019 Oct;56(10):7249. doi: 10.1007/s12035-019-01726-2. Mol Neurobiol. 2019. PMID: 31410736 Free PMC article.
Microbubbles Containing Lysolipid Enhance Ultrasound-Mediated Blood-Brain Barrier Breakdown In Vivo.
Vince O, Peeters S, Johanssen VA, Gray M, Smart S, Sibson NR, Stride E. Vince O, et al. Among authors: johanssen va. Adv Healthc Mater. 2020 Nov 16:e2001343. doi: 10.1002/adhm.202001343. Online ahead of print. Adv Healthc Mater. 2020. PMID: 33191662
A novel molecular magnetic resonance imaging agent targeting activated leukocyte cell adhesion molecule as demonstrated in mouse brain metastasis models.
Zarghami N, Soto MS, Perez-Balderas F, Khrapitchev AA, Karali CS, Johanssen VA, Ansorge O, Larkin JR, Sibson NR. Zarghami N, et al. Among authors: johanssen va. J Cereb Blood Flow Metab. 2020 Nov 5:271678X20968943. doi: 10.1177/0271678X20968943. Online ahead of print. J Cereb Blood Flow Metab. 2020. PMID: 33153376 Free article.
Improving Delineation of True Tumor Volume With Multimodal MRI in a Rat Model of Brain Metastasis.
Larkin JR, Simard MA, de Bernardi A, Johanssen VA, Perez-Balderas F, Sibson NR. Larkin JR, et al. Among authors: johanssen va. Int J Radiat Oncol Biol Phys. 2020 Apr 1;106(5):1028-1038. doi: 10.1016/j.ijrobp.2019.12.007. Epub 2020 Jan 17. Int J Radiat Oncol Biol Phys. 2020. PMID: 31959544 Free PMC article.