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Expression of the E6 and E7 genes of human papillomavirus (HPV16) extends the life span of human myoblasts.
Lochm├╝ller H, Johns T, Shoubridge EA. Lochm├╝ller H, et al. Among authors: johns t. Exp Cell Res. 1999 Apr 10;248(1):186-93. doi: 10.1006/excr.1999.4407. Exp Cell Res. 1999. PMID: 10094825
Characterization of the mitochondrial DNA abnormalities in the skeletal muscle of patients with inclusion body myositis.
Horvath R, Fu K, Johns T, Genge A, Karpati G, Shoubridge EA. Horvath R, et al. Among authors: johns t. J Neuropathol Exp Neurol. 1998 May;57(5):396-403. doi: 10.1097/00005072-199805000-00003. J Neuropathol Exp Neurol. 1998. PMID: 9596410
Gene shifting: a novel therapy for mitochondrial myopathy.
Taivassalo T, Fu K, Johns T, Arnold D, Karpati G, Shoubridge EA. Taivassalo T, et al. Among authors: johns t. Hum Mol Genet. 1999 Jun;8(6):1047-52. doi: 10.1093/hmg/8.6.1047. Hum Mol Genet. 1999. PMID: 10332036
Complete restoration of a wild-type mtDNA genotype in regenerating muscle fibres in a patient with a tRNA point mutation and mitochondrial encephalomyopathy.
Shoubridge EA, Johns T, Karpati G. Shoubridge EA, et al. Among authors: johns t. Hum Mol Genet. 1997 Dec;6(13):2239-42. doi: 10.1093/hmg/6.13.2239. Hum Mol Genet. 1997. PMID: 9361028
A novel heteroplasmic tRNAleu(CUN) mtDNA point mutation in a sporadic patient with mitochondrial encephalomyopathy segregates rapidly in skeletal muscle and suggests an approach to therapy.
Fu K, Hartlen R, Johns T, Genge A, Karpati G, Shoubridge EA. Fu K, et al. Among authors: johns t. Hum Mol Genet. 1996 Nov;5(11):1835-40. doi: 10.1093/hmg/5.11.1835. Hum Mol Genet. 1996. PMID: 8923013
Use of myoblast cultures to study mitochondrial myopathies.
Shoubridge EA, Johns T, Boulet L. Shoubridge EA, et al. Among authors: johns t. Methods Enzymol. 1996;264:465-75. doi: 10.1016/s0076-6879(96)64042-7. Methods Enzymol. 1996. PMID: 8965719 No abstract available.
SURF1, encoding a factor involved in the biogenesis of cytochrome c oxidase, is mutated in Leigh syndrome.
Zhu Z, Yao J, Johns T, Fu K, De Bie I, Macmillan C, Cuthbert AP, Newbold RF, Wang J, Chevrette M, Brown GK, Brown RM, Shoubridge EA. Zhu Z, et al. Among authors: johns t. Nat Genet. 1998 Dec;20(4):337-43. doi: 10.1038/3804. Nat Genet. 1998. PMID: 9843204
Repopulation of rho0 cells with mitochondria from a patient with a mitochondrial DNA point mutation in tRNA(Gly) results in respiratory chain dysfunction.
Raha S, Merante F, Shoubridge E, Myint AT, Tein I, Benson L, Johns T, Robinson BH. Raha S, et al. Among authors: johns t. Hum Mutat. 1999;13(3):245-54. doi: 10.1002/(SICI)1098-1004(1999)13:3<245::AID-HUMU9>3.0.CO;2-B. Hum Mutat. 1999. PMID: 10090480
Dietary Echinacea purpurea during murine pregnancy: effect on maternal hemopoiesis and fetal growth.
Chow G, Johns T, Miller SC. Chow G, et al. Among authors: johns t. Biol Neonate. 2006;89(2):133-8. doi: 10.1159/000088795. Epub 2005 Oct 5. Biol Neonate. 2006. PMID: 16210848
The potency of immunomodulatory herbs may be primarily dependent upon macrophage activation.
Groom SN, Johns T, Oldfield PR. Groom SN, et al. Among authors: johns t. J Med Food. 2007 Mar;10(1):73-9. doi: 10.1089/jmf.2006.233. J Med Food. 2007. PMID: 17472470
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