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Brain glycogen serves as a critical glucosamine cache required for protein glycosylation.
Sun RC, Young LEA, Bruntz RC, Markussen KH, Zhou Z, Conroy LR, Hawkinson TR, Clarke HA, Stanback AE, Macedo JKA, Emanuelle S, Brewer MK, Rondon AL, Mestas A, Sanders WC, Mahalingan KK, Tang B, Chikwana VM, Segvich DM, Contreras CJ, Allenger EJ, Brainson CF, Johnson LA, Taylor RE, Armstrong DD, Shaffer R, Waechter CJ, Vander Kooi CW, DePaoli-Roach AA, Roach PJ, Hurley TD, Drake RR, Gentry MS. Sun RC, et al. Among authors: johnson la. Cell Metab. 2021 Jul 6;33(7):1404-1417.e9. doi: 10.1016/j.cmet.2021.05.003. Epub 2021 May 26. Cell Metab. 2021. PMID: 34043942 Free PMC article.
In situ spatial glycomic imaging of mouse and human Alzheimer's disease brains.
Hawkinson TR, Clarke HA, Young LEA, Conroy LR, Markussen KH, Kerch KM, Johnson LA, Nelson PT, Wang C, Allison DB, Gentry MS, Sun RC. Hawkinson TR, et al. Among authors: johnson la. Alzheimers Dement. 2022 Oct;18(10):1721-1735. doi: 10.1002/alz.12523. Epub 2021 Dec 15. Alzheimers Dement. 2022. PMID: 34908231 Free PMC article.
APOE alters glucose flux through central carbon pathways in astrocytes.
Williams HC, Farmer BC, Piron MA, Walsh AE, Bruntz RC, Gentry MS, Sun RC, Johnson LA. Williams HC, et al. Among authors: johnson la. Neurobiol Dis. 2020 Mar;136:104742. doi: 10.1016/j.nbd.2020.104742. Epub 2020 Jan 11. Neurobiol Dis. 2020. PMID: 31931141 Free PMC article.
APOΕ4 lowers energy expenditure in females and impairs glucose oxidation by increasing flux through aerobic glycolysis.
Farmer BC, Williams HC, Devanney NA, Piron MA, Nation GK, Carter DJ, Walsh AE, Khanal R, Young LEA, Kluemper JC, Hernandez G, Allenger EJ, Mooney R, Golden LR, Smith CT, Brandon JA, Gupta VA, Kern PA, Gentry MS, Morganti JM, Sun RC, Johnson LA. Farmer BC, et al. Among authors: johnson la. Mol Neurodegener. 2021 Sep 6;16(1):62. doi: 10.1186/s13024-021-00483-y. Mol Neurodegener. 2021. PMID: 34488832 Free PMC article.
Mitochondrial Metabolism in Major Neurological Diseases.
Zhou Z, Austin GL, Young LEA, Johnson LA, Sun R. Zhou Z, et al. Among authors: johnson la. Cells. 2018 Nov 23;7(12):229. doi: 10.3390/cells7120229. Cells. 2018. PMID: 30477120 Free PMC article. Review.
Lactate supports a metabolic-epigenetic link in macrophage polarization.
Noe JT, Rendon BE, Geller AE, Conroy LR, Morrissey SM, Young LEA, Bruntz RC, Kim EJ, Wise-Mitchell A, Barbosa de Souza Rizzo M, Relich ER, Baby BV, Johnson LA, Affronti HC, McMasters KM, Clem BF, Gentry MS, Yan J, Wellen KE, Sun RC, Mitchell RA. Noe JT, et al. Among authors: johnson la. Sci Adv. 2021 Nov 12;7(46):eabi8602. doi: 10.1126/sciadv.abi8602. Epub 2021 Nov 12. Sci Adv. 2021. PMID: 34767443 Free PMC article.
Lipid Droplets in Neurodegenerative Disorders.
Farmer BC, Walsh AE, Kluemper JC, Johnson LA. Farmer BC, et al. Among authors: johnson la. Front Neurosci. 2020 Jul 29;14:742. doi: 10.3389/fnins.2020.00742. eCollection 2020. Front Neurosci. 2020. PMID: 32848541 Free PMC article. Review.
695 results