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Oxidative stress with an activation of the renin-angiotensin system in human vascular endothelial cells as a novel mechanism of uric acid-induced endothelial dysfunction.
Yu MA, Sánchez-Lozada LG, Johnson RJ, Kang DH. Yu MA, et al. Among authors: johnson rj. J Hypertens. 2010 Jun;28(6):1234-42. J Hypertens. 2010. PMID: 20486275
Uric acid stimulates monocyte chemoattractant protein-1 production in vascular smooth muscle cells via mitogen-activated protein kinase and cyclooxygenase-2.
Kanellis J, Watanabe S, Li JH, Kang DH, Li P, Nakagawa T, Wamsley A, Sheikh-Hamad D, Lan HY, Feng L, Johnson RJ. Kanellis J, et al. Among authors: johnson rj. Hypertension. 2003 Jun;41(6):1287-93. doi: 10.1161/01.HYP.0000072820.07472.3B. Epub 2003 May 12. Hypertension. 2003. PMID: 12743010
Hormonal and cytokine effects of uric acid.
Sánchez-Lozada LG, Nakagawa T, Kang DH, Feig DI, Franco M, Johnson RJ, Herrera-Acosta J. Sánchez-Lozada LG, et al. Among authors: johnson rj. Curr Opin Nephrol Hypertens. 2006 Jan;15(1):30-3. doi: 10.1097/01.mnh.0000199010.33929.7f. Curr Opin Nephrol Hypertens. 2006. PMID: 16340663 Review.
Effect of lowering uric acid on renal disease in the type 2 diabetic db/db mice.
Kosugi T, Nakayama T, Heinig M, Zhang L, Yuzawa Y, Sanchez-Lozada LG, Roncal C, Johnson RJ, Nakagawa T. Kosugi T, et al. Among authors: johnson rj. Am J Physiol Renal Physiol. 2009 Aug;297(2):F481-8. doi: 10.1152/ajprenal.00092.2009. Epub 2009 May 20. Am J Physiol Renal Physiol. 2009. PMID: 19458127 Free PMC article.
Uric acid: more to learn, more experiments to do.
Johnson RJ, Rivard C, Nakagawa T, Sautin YY, Sanchez-Lozada LG. Johnson RJ, et al. Am J Hypertens. 2009 Sep;22(9):952-3. doi: 10.1038/ajh.2009.117. Am J Hypertens. 2009. PMID: 19701166 No abstract available.
Relationship between uric acid and subtle cognitive dysfunction in chronic kidney disease.
Afsar B, Elsurer R, Covic A, Johnson RJ, Kanbay M. Afsar B, et al. Among authors: johnson rj. Am J Nephrol. 2011;34(1):49-54. doi: 10.1159/000329097. Epub 2011 Jun 10. Am J Nephrol. 2011. PMID: 21659739 Free PMC article.
Uric acid, renal vasoconstriction and erythropoietin relationship in IgA nephropathy revealed by dopamine-induced glomerular filtration response.
Sulikowska B, Johnson RJ, Odrowąż-Sypniewska G, Manitius J. Sulikowska B, et al. Among authors: johnson rj. Kidney Blood Press Res. 2012;35(3):161-6. doi: 10.1159/000330717. Epub 2011 Nov 24. Kidney Blood Press Res. 2012. PMID: 22116260
REPLY TO: Serum uric acid still carries controversies about its role in endothelial dysfunction.
Kanbay M, Turak O, Johnson RJ. Kanbay M, et al. Among authors: johnson rj. J Clin Hypertens (Greenwich). 2013 Apr;15(4):297. doi: 10.1111/jch.12078. Epub 2013 Feb 12. J Clin Hypertens (Greenwich). 2013. PMID: 23551732 No abstract available.
Uric Acid and Left Ventricular Hypertrophy: A Potentially New Modifiable Target?
Kuwabara M, Sato Y, Kanbay M, Johnson RJ. Kuwabara M, et al. Among authors: johnson rj. Am J Hypertens. 2017 Mar 1;30(3):229-231. doi: 10.1093/ajh/hpw195. Am J Hypertens. 2017. PMID: 28096149 No abstract available.
Uric Acid Is a Strong Risk Marker for Developing Hypertension From Prehypertension: A 5-Year Japanese Cohort Study.
Kuwabara M, Hisatome I, Niwa K, Hara S, Roncal-Jimenez CA, Bjornstad P, Nakagawa T, Andres-Hernando A, Sato Y, Jensen T, Garcia G, Rodriguez-Iturbe B, Ohno M, Lanaspa MA, Johnson RJ. Kuwabara M, et al. Among authors: johnson rj. Hypertension. 2018 Jan;71(1):78-86. doi: 10.1161/HYPERTENSIONAHA.117.10370. Epub 2017 Dec 4. Hypertension. 2018. PMID: 29203632 Free PMC article.
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