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404 results
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HIF-1 as a target for drug development.
Giaccia A, Siim BG, Johnson RS. Giaccia A, et al. Among authors: johnson rs. Nat Rev Drug Discov. 2003 Oct;2(10):803-11. doi: 10.1038/nrd1199. Nat Rev Drug Discov. 2003. PMID: 14526383 Review.
HIF-1α induction suppresses excessive lipid accumulation in alcoholic fatty liver in mice.
Nishiyama Y, Goda N, Kanai M, Niwa D, Osanai K, Yamamoto Y, Senoo-Matsuda N, Johnson RS, Miura S, Kabe Y, Suematsu M. Nishiyama Y, et al. Among authors: johnson rs. J Hepatol. 2012 Feb;56(2):441-7. doi: 10.1016/j.jhep.2011.07.024. Epub 2011 Sep 5. J Hepatol. 2012. PMID: 21896344
Endothelial cell HIF-1α and HIF-2α differentially regulate metastatic success.
Branco-Price C, Zhang N, Schnelle M, Evans C, Katschinski DM, Liao D, Ellies L, Johnson RS. Branco-Price C, et al. Among authors: johnson rs. Cancer Cell. 2012 Jan 17;21(1):52-65. doi: 10.1016/j.ccr.2011.11.017. Cancer Cell. 2012. PMID: 22264788 Free PMC article.
Hif-1alpha regulates differentiation of limb bud mesenchyme and joint development.
Provot S, Zinyk D, Gunes Y, Kathri R, Le Q, Kronenberg HM, Johnson RS, Longaker MT, Giaccia AJ, Schipani E. Provot S, et al. Among authors: johnson rs. J Cell Biol. 2007 May 7;177(3):451-64. doi: 10.1083/jcb.200612023. Epub 2007 Apr 30. J Cell Biol. 2007. PMID: 17470636 Free PMC article.
HIF-1alpha controls extracellular matrix synthesis by epiphyseal chondrocytes.
Pfander D, Cramer T, Schipani E, Johnson RS. Pfander D, et al. Among authors: johnson rs. J Cell Sci. 2003 May 1;116(Pt 9):1819-26. doi: 10.1242/jcs.00385. J Cell Sci. 2003. PMID: 12665562
Loss of HIF-1alpha in endothelial cells disrupts a hypoxia-driven VEGF autocrine loop necessary for tumorigenesis.
Tang N, Wang L, Esko J, Giordano FJ, Huang Y, Gerber HP, Ferrara N, Johnson RS. Tang N, et al. Among authors: johnson rs. Cancer Cell. 2004 Nov;6(5):485-95. doi: 10.1016/j.ccr.2004.09.026. Cancer Cell. 2004. PMID: 15542432
A novel role for the hypoxia inducible transcription factor HIF-1alpha: critical regulation of inflammatory cell function.
Cramer T, Johnson RS. Cramer T, et al. Among authors: johnson rs. Cell Cycle. 2003 May-Jun;2(3):192-3. Cell Cycle. 2003. PMID: 12734422 Review. No abstract available.
Inhibition of PPAR gamma 2 gene expression by the HIF-1-regulated gene DEC1/Stra13: a mechanism for regulation of adipogenesis by hypoxia.
Yun Z, Maecker HL, Johnson RS, Giaccia AJ. Yun Z, et al. Among authors: johnson rs. Dev Cell. 2002 Mar;2(3):331-41. doi: 10.1016/s1534-5807(02)00131-4. Dev Cell. 2002. PMID: 11879638
HIF isoforms in the skin differentially regulate systemic arterial pressure.
Cowburn AS, Takeda N, Boutin AT, Kim JW, Sterling JC, Nakasaki M, Southwood M, Goldrath AW, Jamora C, Nizet V, Chilvers ER, Johnson RS. Cowburn AS, et al. Among authors: johnson rs. Proc Natl Acad Sci U S A. 2013 Oct 22;110(43):17570-5. doi: 10.1073/pnas.1306942110. Epub 2013 Oct 7. Proc Natl Acad Sci U S A. 2013. PMID: 24101470 Free PMC article.
Transgenic models to understand hypoxia-inducible factor function.
Doedens A, Johnson RS. Doedens A, et al. Among authors: johnson rs. Methods Enzymol. 2007;435:87-105. doi: 10.1016/S0076-6879(07)35005-2. Methods Enzymol. 2007. PMID: 17998050 Review.
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