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87 results
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A semi-mechanistic model to predict the effects of liver cirrhosis on drug clearance.
Johnson TN, Boussery K, Rowland-Yeo K, Tucker GT, Rostami-Hodjegan A. Johnson TN, et al. Clin Pharmacokinet. 2010 Mar;49(3):189-206. doi: 10.2165/11318160-000000000-00000. Clin Pharmacokinet. 2010. PMID: 20170207
A comparison of the ontogeny of enterocytic and hepatic cytochromes P450 3A in the rat.
Johnson TN, Tanner MS, Tucker GT. Johnson TN, et al. Biochem Pharmacol. 2000 Dec 1;60(11):1601-10. doi: 10.1016/s0006-2952(00)00485-8. Biochem Pharmacol. 2000. PMID: 11077042
Enterocytic CYP3A4 in a paediatric population: developmental changes and the effect of coeliac disease and cystic fibrosis.
Johnson TN, Tanner MS, Taylor CJ, Tucker GT. Johnson TN, et al. Br J Clin Pharmacol. 2001 May;51(5):451-60. doi: 10.1046/j.1365-2125.2001.01370.x. Br J Clin Pharmacol. 2001. PMID: 11422003 Free PMC article.
The development of drug metabolising enzymes and their influence on the susceptibility to adverse drug reactions in children.
Johnson TN. Johnson TN. Toxicology. 2003 Oct 1;192(1):37-48. doi: 10.1016/s0300-483x(03)00249-x. Toxicology. 2003. PMID: 14511902 Review.
Modelling approaches to dose estimation in children.
Johnson TN. Johnson TN. Br J Clin Pharmacol. 2005 Jun;59(6):663-9. doi: 10.1111/j.1365-2125.2005.02429.x. Br J Clin Pharmacol. 2005. PMID: 15948929 Free PMC article. Review.
Changes in liver volume from birth to adulthood: a meta-analysis.
Johnson TN, Tucker GT, Tanner MS, Rostami-Hodjegan A. Johnson TN, et al. Liver Transpl. 2005 Dec;11(12):1481-93. doi: 10.1002/lt.20519. Liver Transpl. 2005. PMID: 16315293
Prediction of the clearance of eleven drugs and associated variability in neonates, infants and children.
Johnson TN, Rostami-Hodjegan A, Tucker GT. Johnson TN, et al. Clin Pharmacokinet. 2006;45(9):931-56. doi: 10.2165/00003088-200645090-00005. Clin Pharmacokinet. 2006. PMID: 16928154
The problems in scaling adult drug doses to children.
Johnson TN. Johnson TN. Arch Dis Child. 2008 Mar;93(3):207-11. doi: 10.1136/adc.2006.114835. Epub 2007 Mar 15. Arch Dis Child. 2008. PMID: 17363397
Intestinal metabolism and transport of drugs in children: the effects of age and disease.
Johnson TN, Thomson M. Johnson TN, et al. J Pediatr Gastroenterol Nutr. 2008 Jul;47(1):3-10. doi: 10.1097/MPG.0b013e31816a8cca. J Pediatr Gastroenterol Nutr. 2008. PMID: 18607262 Review.
Assessing the efficiency of mixed effects modelling in quantifying metabolism based drug-drug interactions: using in vitro data as an aid to assess study power.
Johnson TN, Kerbusch T, Jones B, Tucker GT, Rostami-Hodjegan A, Milligan PA. Johnson TN, et al. Pharm Stat. 2009 Jul-Sep;8(3):186-202. doi: 10.1002/pst.373. Pharm Stat. 2009. PMID: 19291743
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