Johnson WH - Search Results

1

Ro 32-3555, an orally active collagenase inhibitor, prevents cartilage breakdown in vitro and in vivo.

Lewis EJ, Bishop J, Bottomley KM, Bradshaw D, Brewster M, Broadhurst MJ, Brown PA, Budd JM, Elliott L, Greenham AK, Johnson WH, Nixon JS, Rose F, Sutton B, Wilson K. Lewis EJ, et al. Among authors: johnson wh. Br J Pharmacol. 1997 Jun;121(3):540-6. doi: 10.1038/sj.bjp.0701150. Br J Pharmacol. 1997. PMID: 9179398 Free PMC article.

2

(E)-2(R)-[1(S)-(Hydroxycarbamoyl)-4-phenyl-3-butenyl]-2'-isobutyl-2'-(methanesulfonyl)-4-methylvalerohydrazide (Ro 32-7315), a selective and orally active inhibitor of tumor necrosis factor-alpha convertase.

Beck G, Bottomley G, Bradshaw D, Brewster M, Broadhurst M, Devos R, Hill C, Johnson W, Kim HJ, Kirtland S, Kneer J, Lad N, Mackenzie R, Martin R, Nixon J, Price G, Rodwell A, Rose F, Tang JP, Walter DS, Wilson K, Worth E. Beck G, et al. J Pharmacol Exp Ther. 2002 Jul;302(1):390-6. doi: 10.1124/jpet.302.1.390. J Pharmacol Exp Ther. 2002. PMID: 12065742

3

Potent collagenase inhibitors prevent interleukin-1-induced cartilage degradation in vitro.

Nixon JS, Bottomley KM, Broadhurst MJ, Brown PA, Johnson WH, Lawton G, Marley J, Sedgwick AD, Wilkinson SE. Nixon JS, et al. Among authors: johnson wh. Int J Tissue React. 1991;13(5):237-41. Int J Tissue React. 1991. PMID: 1666894

4

Structure of the catalytic domain of human fibroblast collagenase complexed with an inhibitor.

Borkakoti N, Winkler FK, Williams DH, D'Arcy A, Broadhurst MJ, Brown PA, Johnson WH, Murray EJ. Borkakoti N, et al. Among authors: johnson wh. Nat Struct Biol. 1994 Feb;1(2):106-10. doi: 10.1038/nsb0294-106. Nat Struct Biol. 1994. PMID: 7656013

5

Inhibition of bovine nasal cartilage degradation by selective matrix metalloproteinase inhibitors.

Bottomley KM, Borkakoti N, Bradshaw D, Brown PA, Broadhurst MJ, Budd JM, Elliott L, Eyers P, Hallam TJ, Handa BK, Hill CH, James M, Lahm HW, Lawton G, Merritt JE, Nixon JS, Röthlisberger U, Whittle A, Johnson WH. Bottomley KM, et al. Among authors: johnson wh. Biochem J. 1997 Apr 15;323 ( Pt 2)(Pt 2):483-8. doi: 10.1042/bj3230483. Biochem J. 1997. PMID: 9163342 Free PMC article.

6

Matrix metalloproteinase inhibitors in arthritis.

Bottomley KM, Johnson WH, Walter DS. Bottomley KM, et al. Among authors: johnson wh. J Enzyme Inhib. 1998 Apr;13(2):79-101. doi: 10.3109/14756369809035829. J Enzyme Inhib. 1998. PMID: 9629530 Review. No abstract available.

7

The effect of a peptide aldehyde reversible inhibitor of elastase on a human leucocyte elastase-induced model of emphysema in the hamster.

Kennedy AJ, Cline A, Ney UM, Johnson WH, Roberts NA. Kennedy AJ, et al. Among authors: johnson wh. Eur J Respir Dis. 1987 Nov;71(5):472-8. Eur J Respir Dis. 1987. PMID: 3443167

8

Characterization of a tight-binding MMP-3 inhibitor using improved fluorescence spectroscopy techniques.

Finch-Arietta M, Johnson W, Lusch L, Fotouhi N, Walsky R, Hanglow AC. Finch-Arietta M, et al. Agents Actions. 1993;39 Spec No:C189-91. doi: 10.1007/BF01972762. Agents Actions. 1993. PMID: 8273564

9

Collagenase inhibitors: their design and potential therapeutic use.

Johnson WH, Roberts NA, Borkakoti N. Johnson WH, et al. J Enzyme Inhib. 1987;2(1):1-22. doi: 10.3109/14756368709030352. J Enzyme Inhib. 1987. PMID: 2854154 Review. No abstract available.

10

A mutagenic analysis of NahE, a hydratase-aldolase in the naphthalene degradative pathway.

Lancaster EB, Johnson WH Jr, LeVieux JA, Hardtke HA, Zhang YJ, Whitman CP. Lancaster EB, et al. Among authors: johnson wh jr. Arch Biochem Biophys. 2023 Jan 1;733:109471. doi: 10.1016/j.abb.2022.109471. Epub 2022 Nov 26. Arch Biochem Biophys. 2023. PMID: 36522814 Free PMC article.

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